Diuretics questions Flashcards

1
Q

if no hypokalemia, what is drug? (more than one)

A

Amiloride, Triamterene, Spironolactone?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What drugs are used when pt has bipolar disorder/lithium use? (2)

A

Amiloride, triamterene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

between amiloride and triamterene, which is nephrotoxic?

A

triamterene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

which K+ sparing diuretic can be used in CHF

A

Spironolactone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

which K+ sparing diuretic is preferred in cirrhosis

A

Spironolactone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the only class that causes K= wasting with mtb acidosis!

A

CA inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which drug class causes hypercalcemia? hypocalcemia

A
hyper = thiazides
hypo = loop
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which class requires good GFR and which does not?

A

Needs good GFR = Thiazides

Does not need good GFR = Loop

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which Diuretics Can Exacerbate Gout

A

Loop, Thiazides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which diuretic blocks the effect of aldosterone on the heart

A

spironolactone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which 2 actions of Diuretics Cause Kidney Stones?

A

Those that increase pH of urine

Those that increase calcium excretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which diuretics increase calcium excretion

A

loops

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which diuretics ncrease pH of urine

A

CA inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which diuretics treat Kidney stones and MOA

A

MOA: increase reab of clacium

Thiazides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which cause ototoxicity and MOA

A

Loops

MOA: inhibit NKCC transporter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which diuretic is used for a patient with pulmonary edema and/ or
decreased renal function?

17
Q

Sam is a 67 year old man who has had poorly controlled hypertension for the past 15 years, and now presents with signs of ankle edema, a low GFR and a serum creatinine of 2.5 mg/dL. The most effective drug for producing a diuresis and fall in blood pressure in DM is:

A

furosemide

18
Q

Which drug reduces mortality by ~30% in patients with heart failure and liver dysfunction that develops after a myocardial infarction?

A

spironolactone

19
Q

What side effects do you warn them about spironolactone (3)?

A

Impotence
Reduced libido
gynecomastia

20
Q

Gertrude is a 65 year old woman that has been diagnosed with hypercalcemia related to a parathyroid hormone secreting tumor. In addition to her chemotherapy what other drug do you put her on? What side effect do you warn her about?

A

furosemide

ototoxicity

21
Q

What diuretic drug acts on the proximal tubule, is not that good at blocking Na+ reabsorption, but is useful for treatment of glaucoma and acute mountain sickness?

A

acetazolamide

22
Q

Which drug class prodices rise in LDL and decreases glucose tolerance

23
Q

Which is the most useful agent for the treatment of recurrent calcium stones?

24
Q

Which class ADEs: Elevated plasma uric acid and triglycerides

25
Which diuretic would you use in a patient with cerebral edema??
mannnitol
26
Cix fro mannitol
active bleeding
27
A 70 year old woman complains of paresthesias and occasional nausea associated with one of her drugs. She is found to have hyperchloremic metabolic acidosis. She is probably taking
acetazolamide
28
which drug classes cause hyperuricemia (2)
loops, thiazides