Class: Chlamydia Flashcards
Where does chlamydia live inside host (intra- or extracellular)
obligate intracellular - can’t make its own ATP
What part of cell does chlamydia live in
in the phagolysosome
name the two types and the mnemonic for what part of the life cycle they carry out
Elemental bodies Enter cells (they are extra cellular)
Reticular bodies Replicate (intracellular)
which form has the rigid cell wall
the elementary- suvives outside cell!
what cellular antigen do all chlamydia share
LPS O-antigen
What is MOMP?
a type-specific antigen: a heat labile protein n the surface of Elementary bodies
what stain is used to see the organism itself?
Giemsa stain
What is used for microscopic detection of chlamydial antigens?
: IF
What Serovar causes blindness
Serovars A-C “I See you” = “A -C you”
what is treatment for A-C serovars
doxycycline or azithropmycin
How does A-C serovar infx present
Purulent conjunctivitis in children < 2
What dz do servovars D-K cause in males (1)? females (2)?
males = Nongonococcal urethritis females = cervicitis, PID
What is complications (2) of PID and why?
infertility and ectopic pregnancy dt scarring of fallopian tubes
What is Reiters syndrome (3) and mnemonic
uveitis, urethritis, arthritis
“can’t see, can’t pee, can’t climb a tree”
Tx for serovar D-K
Azithromycin- covers gonorrhea and doxycycline
