disorders of the digestive system Flashcards
term for cold sores in the oral cavity
herpes stomatitis
term for canker sores in the oral cavity
apthous somatitis
trouble swallowing
dysphagia
inner layer that lines the GI tract
mucosa
layer of GI tract that contains blood vessels, glands, and missner’s plexus
submucosa
layer of the GI tract that contains circular & longitudinal muscle, myenteric/auerbach’s plexus, performs peristalsis
muscularis
outter connective tissue layer of the GI tract
serosa
GI tract function: movement through the GI tract
motility
GI tract function: breakdown of food/chyme
digestion
GI tract function: transfer of substances across an epithelial layer either into the GI tract or blood
secretion and absorbption
GI tract function: holding and removing digested substances
storage and elimination
the intrinsic nervous system in the GI system
enteric nervous system
what controls the digestive system
autonomic nerves and hormones
phase of gastric function: regulation by the vagus nerve, lasts around 30 minutes
cephalic phase
phase of gastric function: vagus nerve directly stimulates chief cells to secrete pepsinogen to digest proteins
cephalic phase
phase of gastric function: activation of the vagus nerve indirectly causes the parietal cells to secrete HCL
cephalic phase
phase of gastric function: stimulated by distension of the stomach, chemical nature of chyme
gastric phase
phase of gastric function: goal is to release hydrochloric acid and proteolytic enzymes into the stomach
gastric phase
phase of gastric function: stimulated by peptides, stimulates pepsinogen and acid secretion
gastric phase
phase of gastric function: causes inhibition of gastric activity due to neural reflex and hormones
intenstinal phase
phase of gastric function: stretch of the duodenum inhibits gastric motility and secretion
intenstinal phase
phase of gastric function: fat in the chyme stimulates an inhibitory hormone
intestinal phase
mix of food and acids in the stomach
chyme
chyme in the duodenum stimulates what 3 functions
gastric inhibition, pancreatic secretion, bile secretion
what controls pancreatic juice secretion
secretin and chlolecystokinin
hormone stimulated by a drop in duodenal pH
secretin
hormone stimulated by fats and proteins in the duodenum
cholecystokinin
disorder of oral cavity: caused by herpes simplex type 1
herpes stomatitis
disorder of oral cavity: blisters form, followed by ulceration and hard palate
herpes stomatitis
disorder of oral cavity: virus lies dormant in the nervous system and is activated by stress, trauma, or immunosuppression
herpes stomatitis
disorder of oral cavity: an inflammatory spot in the oral cavity, inside the lips, cheeks, or hard palate
aphthous stomatitis
disorder of oral cavity: common oral mucosal lesion
aphthous stomatitis
disorder of oral cavity: shallow, painful ulcers usually less than 1cm in diameter
aphthous stomatitis
how long do canker sores usually last
7-10 days
the superior third of the esophagus is made of what kind of muscle
striated muscle
what structure is found in the superior third of the esophagus
upper esophageal sphincter
the distal two thirds of the esophagus is made of what kind of muscle
smooth muscle
what does the thoracic esophagus enter the abdomen through to become to abdominal esophagus
esophageal hiatus of the diaphragm
where does the upper part of the lower esophageal sphincter lie
within the diaphragmatic hiatus
what kind of muscle is the lower esophageal sphincter
smooth muscle
where does the lower section of the lower esophageal sphincter lie
intra-abdominally
ligament that helps to maintain the position of the lower esophageal sphincter within the abdominal cavity
phrenoesophageal ligament
where does the phrenoesophageal ligament arise from
the diaphragmatic crura
phase of swallowing: mastication process involving taste, temperature, touch, and proprioceptive senses for the formation of a bolus of the right size and consistency
oral preparatory phase
phase of swallowing: manipulation of the bolus toward the pharynx, triggering the pharyngeal reflex as the bolus enters the pharynx
oral transit phase
phase of swallowing: voluntary, controlled by the cerebral cortex. epiglottis covers the airway during swallowing
oral transit phase
phase of swallowing: a reflex action in which the bolus moves through the pharynx, followed by the pushing of the bolus by the pharyngeal constrictor muscles further into the pharynx, ending with the elevation of the larynx
pharyngeal phase
phase of swallowing: followed by the relaxation of the cricopharyngeal muscle, allowing the bolus to pass into the esophagus
pharyngeal phase
phase of swallowing: under the control of the brainstem and the myenteric plexus
esophageal phase
phase of swallowing: a pareistaltic wave beginning in the pharynx pushes the bolus sequentially from the cervical esophagus down through the lower esophageal sphincter and into the stomach
esophageal phase
term for painful swallowing
odynophagia
disease commonly known as heartburn
gastroesophageal reflux disease (GERD)
aka for heartburn
pyrosis
the backward movement of gastric contents into the lower esophagus
gastroesophageal reflux
most common cause of GERD
incompetence of lower esophageal sphincter
protrusion of a portion of the stomach through the diaphragmatic esophageal hiatus into the thoracic cavity
hiatal hernia
two types of hiatal hernia
sliding and rolling
functions of stomach
store food, initiate digestion, kill bacteria, chyme production
product of parietal cells
HCI and intrinsic factor
product of chief cells
pepsinogen
product of goblet cells
mucus
product of enterochromaffin-like (ECL) cells
histamine, serotonin
product of D cells
somatostatin
product of G cells
gastrin
inflammation of the gastric mucosa, can involve the entire mucosa or just be regional
gastritis
aka for stomach lining
gastric mucosa
stomach disorder caused by oral-fecal or contaminated food/water routes. may cause acute or chronic gastritis
helicobacter pylori
transient inflammation of the gastric mucosa, often caused by an imbalance between the aggressive and defensive factors that maintain the integrity of the gastric mucosa
acute gastritis
what are the three pathological stages of mucosal damage
chronic inflammatory changes, atrophy of stomach lining, mucosal thinning/loss of gastric glands/intenstinal metaplasia
circumscribed ulceration of the mucous membrane of the esophagus, stomach, or duodenum. penedtrates through the muscularis mucosa.
peptic ulcer
type of peptic ulcer: more common, generally benign, affects young people
duodenal ulcer
type of peptic ulcer: experienced during periods of increased stress, can go into remission or exacerbation
duodenal ulcer
type of peptic ulcer: affects older patients, may become malignant
gastric ulcer
hemorrhage, obstruction, perforation, failure to heal, and increased risk of gastric cancer are all complications of what
peptic ulcer disease