Digestive System + Hormones Flashcards

1
Q

Where are proteins broken down?

A

in the stomach and duodenum

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2
Q

Amylase

A

breaks down starch

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3
Q

Lipase

A

breaks down lipids

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4
Q

Lysosyme

A

antimicrobial enzyme that kills some bacteria in the mouth

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5
Q

What is broken down in the mouth by saliva?

A

carbs and lipids

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6
Q

peristalsis

A

smooth muscle contracts to move food

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7
Q

bolus

A

moves from the mouth through the esophagus to the stomach

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8
Q

What causes GERD?

A

a weakened lower espohageal sphincter allows food to move backwards

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9
Q

Which cells secrete gastric acid?

A

parietal stomach cells

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10
Q

What is in gastic acid?

A

HCl and salts

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11
Q

What cells secrete pepsinogen?

A

chief cells of stomach

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12
Q

What does the stomach absorb?

A

Vitamin B1 and water by releasing intrinsic factor

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13
Q

How do the acidic conditions not degrade the stomach?

A

mucous epithelial cells secrete bicarbonate at the stomach’s lining to neutralize the acid

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14
Q

What causes peptic ulcers?

A

H. pylori bacteria found in some members of the population

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15
Q

What moves into the small intenstine?

A

chyme

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16
Q

Villi

A

create folds in the small intestine to increase surface area

made of enterocytes

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17
Q

Enterocytes

A

epithelial cells that line the intestines

contain lots of microvilli brushes

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18
Q

What are the parts of the small intestine in order?

A

duodenum, jejunum, ileum

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19
Q

What happens when chyme reaches the duodenum?

A

small intestine secretes secretin

secretin tells pancreas to secrete bicarbonate

bicarbonate neutralizes the acidic chyme

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20
Q

CCK

A

secreted by the small intestine

stimulates release of digestive enzymes from the pancreas and bile from the liver

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21
Q

Where is bile produced and stored?

A

bile is produced in the liver and stored in the gallbladder

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22
Q

What does bile contain?

A

bile salts, pigments, cholesterol

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23
Q

bile salts

A

amphipathic and can form a miscelle around lipids and aqueous environment

24
Q

What is lipid emulsification? What molecules conduct it?

A

breaking down lipids to expose the greatest surface area to hydrolytic enzymes

bile salts carry out lipid emulsification

25
How does liver detox?
through the hepatic portal
26
hepatic portal
a system of blood vessels with a capillarly bed at each end blood from small intestine enters the hepatic portal before entering the body, allowing for detox
27
Digestive enzymes secreted by pancreas
pancreatic amylase pancreatic lipase proteases
28
How do digestive enzymes move to small intestine from pancrease?
alkaline fluid with the enzymes is secreted into the pancreatic duct
29
exocrine function of pancreas
release enzymes into ductal system
30
endocrine function of pancreas
release hormones into bloodstream
31
Brush border enzymes
secreted by enterocytes further break down molecules prior to absorption
32
What are the parts of the large intestine in order?
cecum, colon, and rectum
33
Where is the appendix?
attached to the cecum of the large intestine
34
What is the main function of the colon?
to absorb H2O from chyme
35
What is feces mostly composed of?
cellulose and water
36
Leptin
secreted by adipose cells and promotes fullness triggered when adipose cells have increase in fatty acid synthesis
37
Ghrelin
secreted by pancreas and stomach when stomach is empty triggers appetite
38
G-cells
secrete gastrin which tells parietal cells to produce gastic acid
39
S-cells
secrete secretin in duodenum and tells pancreas to secrete bicarbonate
40
somatostation
halts all pro-digestion hormones, stalls stomach emptying, halts release of insulin and glucagon, inhibits growth hormone
41
enteric nervous system
branch of autonomic nervous system involved in digestion
42
sucrose is broken into
glucose and fructose
43
maltose is broken into
two glucoses
44
lactose is broken into
glucose and galactose
45
What causes lactose intolerance?
no lactase in small intestine so, lactose is broken down in large intestine by microbiome which produces gas
46
Where does pepsin cleave?
between hydrophobic or aromatic sites
47
Where does trypsin cleave?
at lys or arg
48
Where does trypsin work?
in duodenum
49
How are carbs absorbed into the bloodstream?
through secondary active transport first, Na/K pump creates Na+ concentration gradient when Na+ moves down its concentration gradient, it takes carbs with it
50
Which vitamins are water soluble?
vitamin B and C
51
Vitamin A
retinol important for vision
52
Vitamin D
regulates Ca2+ and phosphate concentrations in blood synthesized by skin from UV exposure
53
What is the functional form of Vitamin D called?
calcitriol
54
Vitamin K
needed for blood clotting
55
Vitamin C
absorbic acid required for collagen synthesis