Digestive Part 3 Flashcards

1
Q

Liver

Exocrine gland: produces____ that emulsifies fat

A

bile

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2
Q

Liver

Endocrine gland: secretes hormones including ____ and ____

A

erythropoietin and thrombopoietin

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3
Q

Processes dietary amino acids, carbohydrates, lipids and vitamins

A

Liver

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4
Q

Synthesizes plasma proteins

A

Liver

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5
Q

Liver

Stores carbohydrates in form of_____
and releases same in form of_____

A

glycogen

glucose

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6
Q

Detoxifies and excretes through bile endogenous and exogenous toxic substances

A

Liver

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7
Q

Eliminates particulate materials from blood by phagocytosis

A

Liver

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8
Q

Liver:

Capsule
More commonly known as_____
Thin, fibroelastic capsule
Covered with mesothelium, except for part that is reflected on inferior surface of diaphragm

A

Glisson capsule

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9
Q

Connective tissue from capsule penetrate organ at porta hepatis
Arborize extensively and divide liver into lobules

A

Septa

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10
Q

Branches of hepatic artery and portal vein and tributaries of bile duct accompany each other at connective tissue septae

A

Septa

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11
Q

Portal triad – branches or tributaries in interlobular connective tissue of:

A

Portal vein
Hepatic artery
Bile duct

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12
Q

Interlobular connective tissue
Portal triad

A

Portal area

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13
Q

Liver cells or

A

hepatocytes

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14
Q

Comprise about 80% of cell population of liver

Perform all metabolic and secretory (exocrine and endocrine) functions of liver

A

Liver cells or hepatocytes

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15
Q

Liver cells or hepatocytes

Lateral surfaces of adjoining hepatocytes form______

A

bile canaliculus

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16
Q

Capillaries travelling between hepatocytes

A

Sinusoids

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17
Q

Two other functionally important cells are found with the sinusoids of hepatic lobules:

A

Kupffer cells
Ito cells

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18
Q

Stellate macrophages
APCs
Remove any bacteria or any debris present in the portal blood

A

Kupffer cells

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19
Q

with small lipid droplets that store vitamin A and other fat -soluble vitamins

A

Hepatic stellate cells (or Ito cells)

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20
Q

produce extracellular matrix (ECM) components and cytokines that help regulate Kupffer cell activity

A

Hepatic stellate cells (or Ito cells)

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21
Q

are located between the hepatocytes and the sinusoids

A

SPACE OF DISSE or Perisinusoidal space

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22
Q

Separates sinusoids from hepatic plates

A

SPACE OF DISSE

23
Q

Contains collagenous and reticular fibers, and microvilli of hepatocytes

A

SPACE OF DISSE

24
Q

contains perisinusoidal cells of Ito

A

Space of disse

25
Lymph drained from Disse drains into the
Space of Mall
26
Space of mall or
Periportal soace
27
CONCEPTS ON ARCHITECTURE OF LIVER
Classical hepatic lobule Portal lobule Hepatic acinus
28
Drains blood from the portal vein and the hepatic artery to the hepatic or the central vein
Classic Hepatic Lobule
29
Drains bile from hepatocytes to the bile duct
Portal Lobule
30
Supplies oxygenated blood to hepatocytes
Hepatic Acinus
31
Polygonal Central vein – occupies center of lobule Hepatic plates (contains the hepatocytes) – radiate outwards Portal area with portal triad – present in three corners of each of hepatic lobule
HEPATIC (CLASSIC) LOBULE
32
Central area is occupied by portal area where portal triad is Within portal lobule, blood flows from center to periphery while glandular secretion (bile) flows from periphery to center of lobule
PORTAL LOBULE
33
Regarded by many as true anatomical and functional unit of liver Smaller than classical hepatic lobule and portal lobule Ellipsoidal and lies between two central veins Emphasizes pathophysiological aspect of liver
HEPATIC ACINUS
34
Both an exocrine and an endocrine gland Both endocrine and exocrine components are in the lobules
Pancreas
35
STROMA of pancreas ________ thin layer of connective tissue ________divide gland into indistinct lobules
Capsule Septa
36
PARENCHYMA of pancreas
Glandular epithelium
37
ENDOCRINE PORTION only ____of pancreas Islets of Langerhans
2%
38
________PORTION Compound tubuloalveolar (tubuloacinous) gland Secretes pancreatic juice
EXOCRINE
39
Pancreas Secretes pancreatic juice About_____ a day contains digestive enzymes for protein, carbohydrate and fat digestion
1.2 liters
40
EXOCRINE PORTION Occupies___% of lobule Secretory portions are called_______
98 pancreatic acini
41
closely-packed low columnar or pyramidal cells rest on basal lamina Synthesize enzymatic components of pancreatic juice in rER Nucleus: round with one or more nucleoli
40-50 Pancreatic acinus
42
Pancreas: Ducts
Intralobular ducts /Intercalated duct Interlobular ducts Pancreatic ducts
43
drains an acinus, squamous or low cuboidal epithelium
Intralobular ducts Intercalated duct
44
Union of intercalated ducts
Interlobular ducts
45
Union of interlobular duct Lined by simple columnar epithelium
Pancreatic ducts
46
To collect, store, concentrate, and expel bile when it is needed for emulsification of fat.
Gallbladder
47
Bile is continually produced by______ and transported via the excretory ducts to the_____ for storage.
liver hepatocytes gallbladder
48
WALL of gallbladder
Mucosa Muscular layer Serosa/adventitia
49
Epithelium of gallbladder
Simple (tall) columnar with microvilli No goblet cells
50
Gallbladder Epithelial invaginations (inpocketings or diverticuli) into the lamina propria and the muscle layer Not glandular in nature
Rokitansky-Aschoff sinuses
51
MUSCULAR LAYER Of gallbladder
Poorly defined Inner, mostly longitudinally oriented fibers Outer, mostly circularly oriented muscles
52
produced by enteroendocrine cells of small intestine Induces contraction of smooth muscles Found in what layer?
Cholecystokinin Muscular layer
53
SEROSA/ADVENTITIA: Gallbladder _____over posterior and inferior surfaces ______in surface associated with liver
Serosa Adventitia