digestion and absorption Flashcards

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1
Q

what enzymes are produced in the salivary glands?

A

salivary amylase

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2
Q

what enzymes are produced in the stomach

A

endopeptidases (eg: pepsin)
exopeptidases

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3
Q

what enzymes are produced in the pancreas?

A

pancreatic amylase
lipases
exopeptidases

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4
Q

what enzymes are produced in the ileum

A

membrane bound dipeptidases
disaccharidases (eg: maltase)

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5
Q

describe the role of the enzymes of the digestive system in the breakdown of starch.

A
  • salivary amylases hydrolyse starch into maltose
  • by hydrolysing glycosidic bonds
  • maltose is hydrolysed into glucose
  • by maltase enzymes in the membrane of the epithelium cell membrane of the ileum
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6
Q

co transport of glucose

A
  • Na ions are actively transported out of epithelial cell into the blood
  • creates a concentration gradient of sodium ions between ileum and epithelial cell
  • Na ions and glucose enter by facilitated diffusion using complementary co transporter proteins
  • Na ions diffuse into the cell down the concentration gradient
  • glucose moves into the cell against its concentration gradient
  • glucose moves into the blood by facilitated diffusion
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7
Q

describe the role of enzymes in the digestion of proteins in a mammal

A
  • hydrolysis of peptide bonds
  • endopeptidases act in middle of polypeptide, producing shorter polypeptide chains
  • exopeptidases act at end of polypeptide to produce amino acids
    -dipeptidases produces two single amino acids, act on dipeptide
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8
Q

describe how amino acids are absorbed from the ileum into the blood

A

Na ions are actively transported out of the epithelial cell into the blood
- creates a concentration gradient between the ileum and the epithelial cell
- Na ions and amino acids enter the epithelial cell via facilitated diffusion
- Na ions move down the concentration gradient
- amino acids move against their concentration gradient
- amino acids move into the blood via faciliated diffusion

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9
Q

bile

A
  • produced in the liver
  • neutralises food
  • emulsifies fat droplets to increase the surface area of lipids for lipase action
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10
Q

lipid digestion and absorption

A

lipid droplets are mixed with bile salts and are emulsified
- small droplets increase SA for faster hydrolysis by lipase
- triglycerides hydrolysed into monoglycerides, glycerol and fatty acids
- bile salts and fatty acids and glycerol form micelles
- micelles make fatty acids more soluble in water and transport FA to epithelial cell membrane
- FA simply diffuse through the cell
- At the SER: FA, glycerol are recombined to form triglycerides
- at golgi body: triglycerides are modified and proteins are added to form lipoproteins (chylomicrons), packaged into vesicles
- chylomicrons transported into lymph vessel by exocytosis

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11
Q

describe the processes involved in the absorption and transport of digested lipid molecules from ileum into the lymph vessels

A
  • micelles contain bile salts and fatty acids
  • make fatty acids more soluble in water
  • carry FA to lining of ileum
  • maintain a higher concentration of FA to the lining of ileum
  • FA absorbed by diffusion
  • triglycerides reformed in cells
  • vesicles move to csm
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12
Q

describe the role of micelles in the absorption of fats into the cells of the ileum

A
  • micelles contain bile salts and fatty acids
  • make fatty acids more soluble in water
  • carry FA to lining of ileum
  • maintain a higher concentration of FA to the lining of ileum
  • FA absorbed by diffusion
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