diagnosis of CVD Flashcards

1
Q

What is the best marker for MI?

A

Troponin

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2
Q

What is the best marker for heart failure?

A

BNP

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3
Q

What causes BNP release?

A

Released by the ventricles upon ventricular stretching and wall stress

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4
Q

What conditions can elevate BNP?

A

Pulmonary disease/right heart stress

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5
Q

What enzymes serve as serum cardiac markers?

A

Total creatine kinase and creatine kinase from heart

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6
Q

What proteins serve as serum cardiac markers?

A

Troponin and myoglobin

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7
Q

Describe total CK as a cardiac marker.

A

CK-MB should be mostly contained in the myocardium, with only up to 5% contributing to total CK. If this percentage is higher, it can indicate an MI.

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8
Q

In an acute MI, total CK rises within ___ and returns to normal by ___, while CK_MB returns to normal by ___

A

3-8 hours, 3-4 days, 2-3 days

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9
Q

How long does troponin stay in the serum?

A

1-2 weeks

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10
Q

What protein enters the blood most quickly following MI? When does it return to normal?

A

Myoglobin; 24 hours

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11
Q

In an acute MI, troponin rises within ___ and returns to normal by ___

A

3-8 hours, 5-10 days

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12
Q

What is the recommended time to obtain treatment for MI?

A

Within 90 minutes

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