Diabetes mellitus Flashcards
Define: diabetes mellitus
chronic condition in which the sufferer is unable to utilse their blood glucose regularly.
Define: insulin
hormone secreted by the pancreas to facilitate uptake of glucose from blood into cells.
in all cases of diabetes…
the process of insulin action is interrupted, causing BGL’s to be too high and cells not functioning normally
Effects of diabetes?
- Poor circulation and CVD: excess glucose in bloodstream can result in blood vessels being damaged and poor circulation. Can cause tingling, cell death, amputation of limbs and increased risk of CVD
- Vision problems and blindness: excess blood glucose can damage blood vessels supplying the eye
- Kidney disease: kidneys must work harder to fulter excess glucose in blood which can lead to kidney damage/disease.
WHy does type 1 diabetes occur?
pancreas not producing enough, if any, insulin to allow glucose from blood to enter cells.
Causes/risk factors of type 1 diabetes?
unknown, but presumed links between genetics and exposure to certain viruses (eg. influenza)
when does type 1 diabetes occur?
any life stage, mainly childhood//youth
how must type 1 diabetics manage their condition?
need to deliver insulin (olden days used needle and syringe, now use pumps)
Need to monitor BGL’s - fluctuations can cause tiredness, confusion and headaches
SPecial attention to diet, exercise abd BW (can affect BGL’s)
WHy does type 2 diabetes occur?
due to the pancreas not producing enough insulin, or the body not using insulin effectively (insulin resistance)
Main risk factor for type 2 diabetes?
being overweight - but relationship unclear. potentially:
cells are more resistant to insulin (and hence fat people are more insulin resistant)
High levels of fat could destroy insulin producing cells, lowering level of insulin available
Being overweight puts strain on the pancreas, as it has tried to produce enough insulin. After time
when does type 2 diabetes occur?
most common in older, often overweight people, but becoming more common in younger people.
how is type 2 diabetes managed?
lifestyle changes (eg. diet, exercise, weight management, sometimes medication)
type 2 diabetes is often associated with…
obesity, CVD, hypertension, high blood cholesterol
potential causes of gestational diabetes?
Occurs as hormones released to assist baby’s growth and development can reduce the
Energy requirements increase over the course of pregnancy – as does insulin needs – so there might not be enough insulin to metabolise glucose.
when does gestational diabetes occur?
occurs during pregnancy (affects 3-8% of women) and goes away after pregnancy.