Diabetes 5 Flashcards
Diabetic neuropathy?
Diabetes can damage the nerves (axonal death associated with segmental demyelination)
How does diabetes lead to demyelination?
high BGC damages blood vessels and poor blood supply leads to decreased oxygen supply to the nerves
Peripheral neuropathy location?
affects the nerves supplying the extremities
Peripheral neuropathy effect?
begins as loss of sensation in the toes, and possibly fingers
can result in numbness or acute pain sensation.
Autonomic neuropathy location?
affects the nerves which supply the internal organs (heart, digestive system etc.
Autonomic neuropathy effect?
disruption in the normal functioning of the organs – irregular BPM, chronic diarrhoea, delayed stomach emptying, bladder problems, impotence, difficulty controlling body temp, sudden drops in blood pressure.
Macrovascular complications result?
Cardiovascular disease and stroke
Diabetics increase of risk for diseases?
2.5* more for heart attack and heart failure, 2* more for stroke
Type 1 diabetics increase of risk for diseases?
4* for heart attack, 4.5* for heart failure and 3.5* for stroke
What can peripheral vascular disease lead to?
Amputations
Cause of diabetic foot disease?
Neuropathy(lack of sensation) and vascular disease cause tissue damage in legs and feet (slow healing of wound)