Development of the Head and Neck Flashcards
How many pharyngeal arches are there?
5 (1,2,3,4,6)
Which cranial nerve is associated with the 1st pharyngeal arch?
Trigeminal (CN V)
Which cranial nerve is associated with the 2nd pharyngeal arch?
Facial (CN VII)
Which cranial nerve is associated with the 3rd pharyngeal arch?
CN IX
Which cranial nerve is associated with the 4th pharyngeal arch?
CN X (superior laryngeal)
Which cranial nerve is associated with the 6th pharyngeal arch?
CN X (recurrent laryngeal)
Which cartilage is associated with the 1st pharyngeal arch?
Meckel’s cartilage (becomes mandible)
Which cartilage is associated with the 2nd pharyngeal arch?
Reichert’s cartilage (stapes, hyoid bone)
Which cartilage is associated with the 4th and 6th pharyngeal arches?
Cartilages of larynx
What does the 1st pharyngeal pouch become?
Eustachian tube and middle ear cavity
What does the 2nd pharyngeal pouch become?
Palatine tonsil
What do the 3rd and 4th pharyngeal pouches become?
PTH gland and thymus
What does the 1st pharyngeal cleft become?
External auditory meatus
How many cranial nerves are associated with pharyngeal arches?
4 - (CNs V, VII, IX and X)
What are muscles of mastication derived from?
Ph Arch 1
What are muscles of facial expression derived from?
Ph Arch 2
What is stylopharyngeus derived from?
Ph Arch 3
What is cricothyroid and pharyngeal constrictor muscles derived from?
Ph Arch 4
What muscles are derived from Ph Arch 6?
Intrinsic muscles of the larynx
Describe the origins of the pituitary gland
Rathke’s pouch - ectoderm - AP
Infudibulum - neuroectoderm - PP
What embryonic structures contribute to the development of the face?
Frontonasal prominence and the 1st and 2nd Ph Arches
What structures in the developing face must fuse to form the upper lip and jaw?
Frontonasal prominence and medial nasal prominence
How does cleft lip and palate arise?
Failure of the frontonasal prominence to fuse with maxillary prominence
How is Treacher-Collins syndrome inherited?
Autosomal dominant
How is Treacher-Collins syndrome characterised?
Hypoplasia of mandible and facial bones
What is Di-George syndrome?
Congenital thymic aplasia and absence of parathyroid glands (3rd and 4th Ph Arches involved)