development of the genital system Flashcards
when does the determination of sex occur ?
at fertilizations (determined by male gamete)
if the germ cells fail to reach the genital ridges
gonads do not
What forms the primitive sex cords ?
coelomic epithelium proliferates and penetrates the mesenchyme to form primitive sex cords
3 contributions to the gonads ?
germ cells (endoderm) coelomic epithelium mesenchymal cells (Ct)
development of the testes is induced by what gene
sry
what does the the sry gene encode
Testis dermining factor (TDF)
What does TDF cause
sex cords proliferate to form testis
cords grow into a network that will give rise to rete testes
tunica albuginea seperates cords from surface epithlieum
seminiferous cords form
seminiferous tubules (sertoli cells and spermatogonia) straight tubules, rete tests and mesenchymal cells
what do mesenchymal cells form
leydig cells that produce testerone in week 8
which gonad develops first
right
descent of the testes is associated with
enlargement of the testes
atrophy of the mesonephric kidney
atrophy of the paramesonephric ducts
enlargement of the processus vaginalis
the gubernaculum attached to the uterus becomes what
ovarian ligament and round ligament of uterus
canal of nuck
persistent processus vaginalis in female
mesonephric duct
duct of the intermediate kidney
paramesonephric duct
a longitudinal derivative of epithleium of the urogenital ridge; cranially the duct opens into the coelomic cavity; caudally the two ducts join and fuse together
the development of the genital ducts is controlled by
TDF
mullerian inhibiting factor
produced by sertoli cells and inhibit development of the mullerian duct
testosterone
produced by leydig cells and stimulate continued development of the mullerian duct
the mesoneprhic duct gives rise to
epididymis, ductus deferens, ejaculatory duct and seminal vesicle
in males the _________ regresses and the ________ perisists
mullerian, mesonephric
what are the remnants of mullerian ducts
appendix of testi (paradidymuss) and protatic utricle
paramesonephric duct gives rise to what in females
uterine tube, uterus and superior part of vagina
remnants of the mesonephric ducts in females
epoophoron+ paraoophoron and the gartner’s cyst
gartner’s syst
scattering of tiny remnants of the mesonephric duct that remain near the vagina