Development: Musculoskeletal/Integumentary System Flashcards
Intramembranous bone formation
Pre-existing membranous sheaths
flat bones
Endochondral bone formation
Cartilaginous models
Long bones
Condrification centers
Intramembranous Ossification
High vascular and dense mesenchyme
Osteoblasts
Haversian System
Osteoclasts
Bone Marrow
Intracartilaginous Ossification
Cartilage model
Primary center of ossification
Hemopoietic cells
Epiphyses
Complete by age 20
Time period of Joint development
week 6-8
Fibrous joint development
differentiation into dense fibrous tissue
Cartilaginous joint development
differentiation into hyaline or fibrocartilage
Synovial Joint development
peripheral formation capsule
central cavitation
formation of synovial lining
Week 4 Development
Vertebral column
Sclerotomes surround notochord and neural tube
Membranous Development bones
typically flat bones of skull and sutures
Week 5 development
limb buds appear
Week 8 development
primary centers of ossification
Week 34-38
secondary centers of ossification
Development of smooth muscle
splanchnic mesenchyme around endoderm of primitive gut
Development of cardiac muscle
from primordial myocardium
growth & differentiation of single cells
Anomalies of Limbs
24-36 days of critical period in limb development
Amelia
complete lack of limb development
Meromelia
Short limbs present, useless
Polydactyly
extra digits in fingers or toes
Syndactyly
fusion of two digits in fingers or toes
Congenital Clubfoot
position of feet/ankles turned medially
caused by too little amniotic fluid
Congenital Hip Disclocation
acetabulum development issues
Serious Limb Anomalies
Amelia
Meromelia
Cosmetic Limb Anomalies
Polydactyly
Syndactyly
Mechanical Limb Anomalies
Congenital Club Foot
Congenital Hip Disclocation
Skin Development
Surface Ectoderm (Epidermis)
Mesoderm (Dermis)
Neural Crest (Melanocytes)
