Determinants of Health and Disease Flashcards
Define a stress
an external factor which exerts a disadvantageous effect on the organism.
Define a strain
a reduction in function resulting from a stress.
Define adaptation.
changes in function between individuals due to evolution, in order to change (the magnitude of) the response to a stress. Adaptation involves heritable changes in DNA structure.
Define Acclimatisation
physiological changes made during the life of the individual due to stresses to ameliorate strain. This is genetically determined but does not cause changes in the DNA.
What model is the western medicine centred around?
Western medicine has been centered around the biomedical model.
What are healthy and unhealthy people defined as in the biomedical model?
According to the biomedical model, a healthy person is defined as someone free from any disease whereas an unhealthy person is defined as someone with any symptoms of any disease.
How does the biomedical model veiw disease?
It views disease as a breakdown of body systems or other bodily function, or caused by specific pathogenic agents being introduced to the body.
How does the biomedical model help people with disease?
It examines the body for “broken parts” and aims to restore these parts to function normally by supporting or replacing these functions.
What is the methodology of the biomedical model?
The biomedical model therefore focuses more on testing and diagnosing underperforming functions and then treating them.
Treatment under the biomedical model falls under three main categories which are:
- Surgery.
-Generally successful - Structure restored or reformed
- Antibiotics
- Very successful
- Structure often repaired after pathogen killed
- Pharmaceutical drugs
- Generally do not repair structure/function – so healing does not occur
What do pharmaceutical drugs do?
They tend to either replace the function or reduce the symptom.
The result is often that individuals will have to take them for the rest of their life.
They commonly have unwanted side effects.
Modes of action of pharmaceutical drugs:
- Physical mechanisms
e.g. Emollients - Chemical mechanisms
e.g. Antacids - Drug- receptor interactions
e.g. Insulin - Drug- enzyme interactions
e.g. Aspirin - Drug- channel interactions
e.g. Calcium channel blockers (some blood pressure medications)
Has the biomedical model really helped us to live longer?
Well, an analysis of the mid-Victorian period shows life expectancy at age 5 was as good as or even better than the life expectancy we have today, even though we are more medically advanced, so if anything life expectancy has shortened since this era. Incidences of degenerative diseases was 10% of ours. There level of physical activity was twice ours today. Perhaps factors such as this are the reason why they have a longer life expectancy than us even without the medication. As long as we look after our bodies throughout our entire life, we may no longer need medicines in later years of life (age 60-70). However, medicine CAN keep us alive for slightly longer, but we live in poor health. On average women are now living for 19.1 years in
poor health, compared with 16.1 years for men.
What does functional medicine aim to do?
The aim is to restore function by looking at and understanding the root cause of the issue, not just addressing symptoms of it.
What are some pre-requisites for human health?
– Peace
* Shelter
* Education
* Food
* Income
* A stable eco-system
* Sustainable resources
* Social justice and equity