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Pharmacology Exam > Dermatology > Flashcards

Dermatology Flashcards

1
Q

Isotretinoin

A
  • Retinoid- oral- selective/ non-selective
  • Cystic acne vulgaris, chemo agent
  • Pregnancy Category X
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2
Q

Tretinoin

A
  • Retinoid- topical- decreases adhesiveness of epithelial cells, stimulation of mitotic activity/cell turnover
  • Highly flammable
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3
Q

Benzoyl peroxide

A
  • Topical- Antibacterial action against acnes
  • AE- redness, dryness, itching
  • Avoid excess sunlight
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4
Q

Sulfacetamide

A
  • Topical- PABA antagonist, inhibits bacterial growth
  • Acne vulgaris, acne rosacea, seb dermatitis
  • CI for sulfur allergy
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5
Q

Clobetasol propionate

A
  • Topical steroid
  • Eczema and psoriasis
  • BLACK BOX- systemic absorption can cause reversible HPA axis suppression
  • SE- cushing’s, hyperglycemia, skin thinning
  • CI use in children under age 2
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6
Q

Fluocinonide

A
  • Topical steroid
  • Eczema and psoriasis
  • BLACK BOX- systemic absorption can cause reversible HPA axis suppression
  • SE- cushing’s, hyperglycemia, skin thinning
  • CI use in children under age 2
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7
Q

Mometasone

A
  • Topical steroid
  • Eczema and psoriasis
  • BLACK BOX- systemic absorption can cause reversible HPA axis suppression
  • SE- cushing’s, hyperglycemia, skin thinning
  • CI use in children under age 2
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8
Q

Fluticasone

A
  • Topical steroid
  • Eczema and psoriasis
  • BLACK BOX- systemic absorption can cause reversible HPA axis suppression
  • SE- cushing’s, hyperglycemia, skin thinning
  • CI use in children under age 2
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9
Q

Triamcinolone

A
  • Topical steroid
  • Eczema and psoriasis
  • BLACK BOX- systemic absorption can cause reversible HPA axis suppression
  • SE- cushing’s, hyperglycemia, skin thinning
  • CI use in children under age 2
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10
Q

Hydrocortisone

A
  • Topical steroid
  • Eczema and psoriasis
  • BLACK BOX- systemic absorption can cause reversible HPA axis suppression
  • SE- cushing’s, hyperglycemia, skin thinning
  • CI use in children under age 2
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11
Q

Calcipotriol

A
  • Synthetic Vit D3
  • Plaque psoriasis, Topical- dermatitis
  • CI hypercalcemia, Vit D toxicity
  • DO NOT USE ON FACE
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12
Q

Selenium sulfate

A
  • Reduces corneocyte production
  • OTC and Rx
  • Dandruff, tinea versicolor
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13
Q

Mupirocin

A
  • Skin infection
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14
Q

Triple antibiotic

A
  • Bacitracin, neomycin, polymycin B

- Skin infection

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15
Q

Nystatin

A
  • Skin infection
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16
Q

Imiquimod

A
  • Warts, external genital warts, actinic keratosis, superficial BCC
  • DO NOT USE with immunocompromise or kids with mulluscum
17
Q

Diclofenac gel

A
  • NSAID, Topical pain relief
18
Q

Capsaicin

A
  • Depletes supstance P, Topical pain relief
19
Q

Botulinum toxin

A
  • Blocks ACh release
  • OAB, chronic migrain, limb spasticity, hyperhidrosis, wrinkles
  • AE- weakness, breathing difficuty
  • BLACK BOX- distant spread of toxin effect (hours to weeks)
20
Q

Cyclosporine

A
  • Occular emulsant, drops

- Chronically dry eyes, ocular inflammation, sjogren’s scleroderma

21
Q

Sulfacetamide

A
  • Bacteriostatic

- Eye infection, conjuctivitis, superficial ocular infection

22
Q

Gentamicin

A
  • Conjuctivitis, Keratitis, corneal ulcer, blepharitis, acute meibomianitis, dacrocystitis, amino glycoside
  • OXOTOXICITY
23
Q

Erythromycin

A
  • Superficial ocular infection of conjuctiva/cornea
24
Q

Latamoprost

A
  • Prostaglandin analogue- receptor agonist- increases aqueous humor outflow
  • open angle glaucoma, ocular HTN
  • BLACK BOX- increased pigmentation of iris, eyelids, eyelashes
25
Q

Timolol

A
  • Non-selective BB
  • Open angle claucoma, ocular HTN
  • CI/AE- same as BB
  • BLACK BOX- potential for systemic absorption
26
Q

Pilocarpine

A
  • Cholinergic agonist, parasympathomimetic, causes miosis, decrease pressure in open angle glaucoma or ocular HTN
  • Sjogren’s/ dry mouth, Acute closed angle
27
Q

Atropine

A
  • Anti-cholinergic- Paralysis of ciliary muscle (cycloplegia)
  • Treatment of functional ambiyopia, heart block, bradycardia, hyperhidrosis
  • AE- increase in BP
28
Q

Nepafenac

A
  • NSAID
  • Pain, inflammation associated with cataract surgery
  • AE- increased bleeding, delayed healing, corneal effects, DON’T WEAR CONTACTS
29
Q

Neomycin + Polymyxin B + Hydrocortisone

A
  • Antibacterials and steroid
  • Otitis externa, mastoidectomy infxns
  • OTOTOXICITY- BLACK BOX- can cause permanent sensorineural hearing loss- Cochlea, organ of corti
30
Q

Olopatadine

A
  • Anti-histamine, Mast cell stabilizer, eye drops
  • occular itching, allgergic conjuctivitis
  • AE- cold like symptoms, pharyngitis
31
Q

Cromolyn sodium

A
  • Anti-histamine, Mast cell stabilizer, oral inhaler
  • Eye, nose
  • AE- N/V/D, urticaria
  • BLACK BOX- decrease does with Kd or Lv dysfunction
32
Q

Oxymetazoline

A
  • Afrin/visine
  • Shrink nasal membranes and nasal.ocular vessels
  • Limit to 3 day use- may cause rebound congestion
33
Q

Phenylephrine

A
  • Sudafed pill/spray
  • Shrink nasal membranes and nasal.ocular vessels
  • Limit to 3 day use- may cause rebound congestion
34
Q

Beciomethasone

A
  • Inhaled steroids- corticosteroids

- Allergies

35
Q

Budesonide

A
  • Inhaled steroids- corticosteroids

- Allergies

36
Q

Fluticasone

A
  • Inhaled steroids- corticosteroids

- Allergies, also formulated for eczema/topical

37
Q

mometasone

A
  • Inhaled steroids- corticosteroids

- Allergies, also formulated for eczema/topical

Pharmacology Exam (12 decks)

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