dermatology Flashcards
what are the different types of eczema ?
atopic - genetic barrier dysfunction seborrheoic - face/scalp discoid - annular patches pomphylx - vesicles on palms/soles varicose - venous insufficiency
what is the pathogenesis of atopic eczema ?
abnormal filaggrin expression
filaggrin binds keratin filaments together, plays role in producing natural moisturising factor
when should allergic eczema be considered ?
immediate reactions - lip swelling, redness
late reactions 24/48 hours after ingestion
GI problems
failure to thrive
severe eczema unresponsive to treatment
severe itching
how do you treat eczema ?
emollients topical steroids calcineurin inhibitors UVB light therapy immunosuppression
what is impetigo ?
common acute superficial bacterial skin infection
pustules and honey-coloured crusted erosions
caused by staph aureus
how do you treat impetigo ?
topical antibiotics - fucidin
oral antibiotics - flucloxacillin
what is molluscum contagiosum ?
common benign self limiting infection, 2wk - 6 month incubation
molluscipox virus
pearly papule, umbilicate centre
can take 24 months to clear
how do you treat molluscum contagiosum ?
potassium hydroxide
what is viral exanthems ?
common association with viral illnesses
fever, malaise, headache
reaction to toxin produced by organism, damage to skin, immune response
what viruses cause viral exanthems ?
chicken pox measles rubella roseola erythema infectiosum
what is hand, foot and mouth disease ?
usually coxsackie virus A16
enterovirus
blisters on areas + viral symptoms
self limiting
what causes erythema nodosum ?
infections - strep, URTI IBD sarcoidosis drugs - OCP, penicillin mycpbacterial infection idiopathic
