DERM - Pigmented lesions Flashcards
fitzpatrick type 1
pale white skin, blue / green eyes, blond / red hair
fitzpatrick type 2
fair skin, blue eyes
fitzpatrick type 3
darker white skin
fitzpatrick type 4
light brown skin
fitzpatrick type 5
brown skin
fitzpatrick type 6
dark brown or black skin
darker white skin
fitzpatrick type 3
brown skin
fitzpatrick type 5
fair skin, blue eyes
fitzpatrick type 2
pale white skin, blue / green eyes, blond / red hair
fitzpatrick type 1
dark brown or black skin
fitzpatrick type 6
light brown skin
fitzpatrick type 4
which fitzpatrick types can still burn?
4-6
what is the ABCDE classification?
Asymmetry Border Color Diameter Evolving
melanocytes are triggered to proliferate by activation of what oncogene?
BRAF
how do atypical nevi differ from common nevi?
- begin to appear near puberty instead of childhood
- continue to develop past fourth decade
what lesion may be part of AMS?
atypical nevi?
are junctional nevi above or below the basement membrane?
above
compound or dermal nevus that forms a white border
halo nevus
where are halo nevi usually found?
trunk (never on hands / feet)
what is responsible for deep pigmentation in halo nevi?
T cells
- cafe au lait appearance with raised black dots in middle
- hairless, oval or irregularly shaped brown lesion, dotted with darker brown to black spots
speckled lentiginous nevus (nevus spilus)
where are beckers nevi found? what is the typically age group?
- shoulder
- submammary area
- upper / lower back
- rarely on lower limbs
adolescent males
where are blue nevi usually seen? can they be melanotic?
- back of hands
- yes
what is idiopathic guttate hypomelanosis?
- white spots on arms and legs
- sharply demarcated borders
- elderly
- melanin absent in basal keratinocytes
what is nevus anemicus?
- white, macular, ill defined border surrounded by smaller lesions
- congenital, localized, pharmacological cutaneous anomaly
- usually on trunk
ephelides aka:
freckles
distinctive cutaneous eruption with reticular pattern related to chronic exposure to heat from wood stove, fireplace, electric blanket, hot water bottle, laptop
erythema abigne
which UV ray causes CT changes seen in photoaging, photocarcinogenesis, and immunosuppression?
UVA
what are the causes of sun damaged skin?
DNA mutations (UVB) and ROS (UVA)
what is polymorphous light eruption?
- most common light induced skin disease
- burning itching erythema often in V of chest, dorsum of hands / forearms, lower leg
