Depressive And Bipolar Disorders Flashcards

1
Q

Illness marked primarily by disturbances in mood, I.e. a persistent emotional state

-Moods can be elevated or depressed

A

Mood disorder

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2
Q

Although the primary symptom of a mood disorder is mood change, symptoms almost always occur in which other 3 types of behavior?

A

Sleep, appetite, and cognition

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3
Q

Characterized by depressed mood, diminished interest/pleasure, and at least 5% change in body weight

A

Major Depression

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4
Q

66% of patients contemplate suicide, with 10-15% completing it

A

Major Depression

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5
Q

The peak incidence of major depression is in the

-Shows cultural differences in expression

A

Depression

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6
Q

May be present as the first episode of eventual bipolar or schizophrenic disorders

A

Depressions

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7
Q

The heritability for major depression appears to be

A

40%

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8
Q

Medical disorders such as drug intoxications and withdrawals, tumors, infections, cerebrovascular and cardiovascular events, etc are part of the differential diagnosis for

A

Major Depression

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9
Q

First episode occurs before 40 in 50% of patients

A

Major Depression

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10
Q

What percentage of patients with initial diagnosis of major depression go on to have a manic episode?

A

5-10%

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11
Q

Dysfunctionalthoughtpatternsandbeliefsabout oneself, the environment and the future may lead painful affects, dysfunctional behaviors and expectation of failure. This in turn can predispose to

A

Depression

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12
Q

A loss of interpersonal connections and efficacy can lead to and perpetuate

A

Depression

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13
Q

Characterized by loss of pleasure in all or almost all activities or lack of reactivity to pleasurable activities

A

Major depression with melancholic features

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14
Q

Major depression with melancholic features must also have

A

Depression worse in the AM

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15
Q

Characterized by mood reactivity AND significant weight gain or increase and appetite, hypersonic, or leaden paralysis

A

Major depression with atypical features

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16
Q

Characterized by mood congruence (self punishment or guilt), and delusions or hallucinations

A

Major Depressive Disorder w/ Psychotic features

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17
Q

Symptoms occur during pregnancy or in the 4 weeks following delivery w/ or w/o psychosis

A

Major depressive disorder w/ peri partum onset

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18
Q

Major depression with peri partum onset may be ore common in the first pregnancy, w/ psychotic features more likely with the

A

Second episode

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19
Q

Depressed mood most of the day for more days than not for at least 2 years

A

Persistent Depressive Disorder

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20
Q

Is never without symptoms over the 2 year period for more than two months

A

Persistent Depressive Disorder

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21
Q

Persistent depressive disorder have a 12 month prevalence of

A

1-2% for chronic depression

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22
Q

There is no clear genetic difference between PDD and

A

Major Depression

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23
Q

About 50% of patients with Persistent Depressive Disorder have symptoms before

A

25 y/o

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24
Q

15% of patients with persistent depressive disorder progress to

A

Bipolar II

25
Q

Marked affective liability, irritability, or interpersonal conflict present in the final week before the onset of menses

-Improve within a few days after onset of menses

A

Premenstrual Dysphoric Depressive Disorder

26
Q

Risk factors include stress, previous trauma, and seasonal changes

A

Premenstrual Dysphoric Depressive Disorder

27
Q

We want to monitor caffeine, sugar, and sodium with?

-Also calcium and B6

A

Premenstrual Dysphoric Depressive Disorder

28
Q

Differential includes substance intoxication and withdrawal, primary depression, or primary depressive disorder due to another medical condition

A

Substance/medication induced depressive disorder

29
Q

Prominent and persistent depressed mood or decreased interest that dominates the clinical picture

-Direct pathophysiological effect of another medical condition

A

Depressive disorder due to another medical condition

30
Q

Clear associations with CVA, Huntington’s, Parkinson’s, TBI, Cushing’s, and hypothyroidism

A

Depressive disorder due to medical condition

31
Q

Cyclothymia is included in the category of

A

Bipolar and related disorders

32
Q

Must meet criteria for manic episode which is preceded by hypomania or major depressive episodes

A

Bipolar Type 1

33
Q

Are depressed for up to 1/3 of their lives

A

Bipolar Patients

34
Q

Elevated, expansive, or irritable mood and persistently increased goal directed activity or energy lasting at least 1 week

A

Manic Episode

35
Q

The difference between hypomania and mania is degree of intensity of symptoms and impairment. Hypomania must last at least

A

4 Days

36
Q

Behavior that is not characteristic of the individual and is observable by others but does not cause marked impairment

A

Hypomanic Episode

37
Q

Presence of at least 4 mood episodes in the previous 12 months that meet criteria for manic, hypomanic or depressive episodes

A

Bipolar/related disorders w/ rapid cycling

38
Q

Shows a period of partial/full remission of at least 2 months

A

Bipolar/related disorders w/ rapid cycling q

39
Q

Has bipolar features but also delusions and hallucinations

A

Bipolar w/ psychotic features

40
Q

Bipolar w/ stupor, catalepsy, waxy flexibility, mutism, and posturing

A

Bipolar w/ catatonia

41
Q

Equal prevalence in men and women, and 83% of cases are classified as severe

A

Bipolar 1 disorder

42
Q

The mean age of onset for bipolar is

A

18

43
Q

What percentage of bipolar 1 patients have depression as the first episode?

A

67-75%

44
Q

Can last for 3 months, and 90% of patients have more than one episode and time between episodes can decrease

A

Bipolar 1

45
Q

Young age of onset, alcohol dependence, psychotic features, and lack of interepisode remission are poor prognosticators for

A

Bipolar 1

46
Q

Is differentiated based on the fact that there is a history of hypomanic, but not manic episodes

A

Bipolar 2

47
Q

5-15% will ultimately develop a manic episode

-Age of onset is mid 20’s

A

Bipolar 2

48
Q

Bipolar 2 shows a decline in

A

Occupational/cognitive abilities

49
Q

Bipolar 2 has a poorer prognosis if there is

A

Rapid Cycling

50
Q

Late age of onset, higher education, and marriage are good prognosticators for

A

Bipolar 2

51
Q

There is mixed data on gender prevalence, but 10-20% of post partum women may experience a

A

Hypomanic Episode

52
Q

Is the lethality of suicide attempts higher in type 1 or type 2 bipolar?

A

Bipolar 2

53
Q

A chronic fluctuating disorder of at least 2 years duration marked by many periods with hypomanic symptoms that don’t meet bipolar criteria and many periods of depressive symptoms that don’t meet criteria for MDD

A

Cyclothymia disorder

54
Q

Different from bipolar 2 in that the depression is not major depression

A

Cyclothymia

55
Q

With cyclothymia, the longest time period that a patient is free of mood swings is

A

2 months

56
Q

50-75% of patients with cyclothymia have an age of onset between

A

15 and 25

57
Q

What percentage of cyclothymia patients have a positive FH for bipolar disorder?

A

About 30%

58
Q

Much more sensitive to be switched to hypomania/mania with antidepressants

A

Cyclothymia Patients

59
Q

Differential always includes Bipolar 1 or 2, substance use disorders, ADD/ADHD and personality disorders

A

Cyclothymia Disorder