Death 1 Flashcards
Innate Immunity
Inborn or non-specific; treats everything the same.
Physical Barriers: skin, mucous, tears, saliva
chemical mediators: chemical lysosomes, HCL, sweat(acid).
Cells: specific phagocytosis and chemical release.
Adaptive Immunity
Knows what it is fighting.
Specificity: knows exactly what its fighting and has an ability to recognize.
Memory: knows if it’s been seen before.
B and T cells
Symptoms of Inflammation (edema)
- pain (activates nerves)
- heat (increase in blood flow)
- redness (increase in blood flow)
- swelling
Interferons
proteins produced by most cells that protect against virus’
Classical Pathway
relies on antibodies
Alternative pathways
not reliant on antibodies; spontaneous skips to C3 direct activation.
Activated complement protein
- macrophage attack
- optimize bacteria to make it more appealing
- chemotaxis and inflammation
surface chemicals
lysozymes (tears, sweat, saliva, nasal secretions)
Lysozymes
get rid of bacteria
Histamine
an amine released from mast cells, basophils and platelets; histamine causes vasodilation, increased vascular permeability, stimulates gland secretion, causes smooth muscle contraction of airway passages in the lungs, and attracts eosinophils.
Kinins
polypeptides that are derived from plasma proteins. They cause vasodilation, increase in vascular permeability, stimulates pain receptors, and attracts neutrophils.
Prostoglandins
a group of lipids that( PGE, PGF, thromboxines, and prostacyclines), some of which cause smooth muscle contraction and vasodilation*, increase vascular permeability, and stimulate pain receptors.
Pyrogens
chemicals released by neutrophils, monocytes and other cells.
** causes fever
Complement
group of plasma proteins that increase vascular permeability, stimulate the release of histamine, activate kinins, lyse cells, promote phagocytosis, and attract neutrophils, monocytes, macrophages, and eosinophils.
Leukotrienes
a group of lipids, produced primarily by mast cells and basophils, that cause prolonged
smooth muscle contraction (especially in the lung bronchioles), increase vascular permeability, and attract neutrophils and eosinophils.