Day 9

Question 1

AED with Broadest Coverage Spectrum

Answer 1

Depakote

Question 2

VPA Mech

Answer 2

Blockage of Vg Na channels and GABA enhancement

Question 3

Oxcarb vs. Carbam Metabolism

Answer 3

Oxcarb doesn’t produce autoinduction

Question 4

TCA Cardiac Conduction (2)

Answer 4

Prolongs both PR and QRS intervals

But can also cause tachycardia

Question 5

L5 Function/Damage

Answer 5

Foot flexion/dorsiflexion. So dropfoot

Question 6

S1 Function

Answer 6

Foot extension

Question 7

L3/L4 Function

Answer 7

Leg extension/quads

Question 8

L1/2/3 Function

Answer 8

Hip flexion/iliopsoas

Question 9

S1 Reflex

Answer 9

Achilles/ankle jerk

Question 10

Vilazodone Mech (2)

Answer 10

5HT 1A partial agonist and SSRI

Question 11

Brown-Sequard Syndrome

Answer 11

Hemisection of spinal cord:
Ipsilateral motor + posterior column (vib/proprio) at level of injury and below
Contralateral loss of pain/temp 1-2 dermatomes below

Question 12

ACA Territory

Answer 12

Medial frontal lobes

Question 13

ACA Stroke Motor

Answer 13

Often preferential leg > face/arms, but still some (& obv contralateral)

Question 14

ACA Ocular

Answer 14

Loss of tonic opposition, so look towards the lesion

Question 15

ACA Stroke Behavior

Answer 15

Abulia/amotivation. So won’t do things independently, maybe mute

Question 16

NE/5HT/DA/ACh origins

Answer 16

NE: Locus ceruleus
5HT: dorsal raphe nuclei
DA: SN
ACh: nucleus basalis of Meynert

Question 17

Pure Sensory Stroke:

Answer 17

Small lesion to ventroposterolateral nucleus of thalamus

Question 18

Hemiballismus Lesion Location

Answer 18

Contralateral subthalamic nucleus of Luys

Question 19

6 Biogenic Amine NTs

Answer 19

DA
Epi
NE
ACh
Histamine
5HT

Question 20

3 Catecholamines (& precursor)

Answer 20

Precursor: Tyrosine
DA
NE
Epi

Question 21

Cocaine and Biogenic Amines

Answer 21

Blocks their reuptake, most specifically 5HT/NE/DA

Question 22

Tyrosine and Tyramine

Answer 22

Tyramine is breakdown product of tyrosine

Question 23

Reserpine Mech

Answer 23

Blocks Mg-dependent uptake of biogenic amines, depleting DA, NE, and 5HT

Question 24

Reserpine Use

Answer 24

Can relieve dystonia

Question 25

Reserpine Sfx (3)

Answer 25

Can cause depression, sedation, and Parkinsonism

Question 26

Arachnoid Granulations (function and histopathological location)

Answer 26

Drain CSF into blood

Protrude through dura into superior sagittal sinus

Question 27

Choroid Plexus (function and histopathological location)

Answer 27

Produce CSF

Protrude into ventricles

Question 28

2 Drugs that Reduce CSF Production

Answer 28

Acetazolamide

Mannitol

Question 29

Regression Analysis

Answer 29

Method of predicting value of one variable in relation to another variable based on observed data