Day 10

Question 1

Suprachiasmatic Nucleus

Answer 1

In hypothalamus, helps with sleep regulation

Question 2

Melatonin Timing

Answer 2

Begins releasing in evening (~8pm), peaks in night (3-5am), then decreases during the day

Question 3

Projective Test

Answer 3

Category of psychological tests where you present incomplete picture/information to patient and they complete it. Reveals aspects of themselves through responses

Question 4

Subacute Sclerosing Panencephalitis (what it is + presentation)

Answer 4

Late complication of measles infecting neurons/glia

Often in children 5-10, presents with spastic/choreoathetoid movements, seizures, behavior changes, etc

Question 5

SSPE 3 Dx Tests

Answer 5

LP/CSF: Measles Ab
Brain Bx: Viral inclusion bodies
EEG: Periodic bursts of generalized slow-wave complexes

Question 6

SSPE Tx + Prognosis

Answer 6

Unclear, but interventricular interferon-alpha + isoprinosine

Question 7

SSPE Prognosis

Answer 7

Very poor, death w/in 1 year if poor response to tx

Question 8

Lesch-Nyhan Syndrome (inheritance pattern, what it is, deficiency)

Answer 8

XLR d/o of purine/pyrimidine metabolism

Deficiency in hypoxanthine-guanine phosphoribosyltransferase results in hyperuricemia

Question 9

Lesch-Nyhan Sx (& cause)

Answer 9

Choreoathetosis, hyperreflexia, hypertonia, self-mutilatory behavior, behavioral disturbances
Likely from decr DA in CNS

Question 10

Gaucher’s Ds (inheritance pattern, deficiency)

Answer 10

AR deficiency in Beta-glucosidase

Question 11

Gaucher’s Sx

Answer 11

Hypersplenism, bone abnormalities, heme abnormalities, skin pigmentation

Question 12

Schizophrenia Active-Phase Sx Time Requirements

Answer 12

1 month (6 mo is once prodrome/neg sx start)