Day 12 Flashcards
Reflex Sympathetic Dystrophy
Injury then leads to crazy sympathetic response in the area, constant pain, and eventually tissue death
Best Predictor for Future Violence
Past Violence
Two CYPS induced by Carbamazepine
2C19 and 3A4
Standard of Substituted Judgment
Surrogate decision maker makes decision based on what patient would have wanted
Risperidone Metabolism
2D6 (so incr by a lot of meds, including some SSRIs like fluoxetine)
Quinidine and Fluoxetine Shared Inhibition
2D6 Inhibitors
Nuedexta
DXM + Quinidine for pseudobulbar affect
FGA that’s lowered by smoking
Haloperidol, bc of smoking’s 1A2 inhibition
Sheehan’s Syndrome (what it is)
Posterior pituitary infarction/apoplexy after birth
Sheehan’s Syndrome 3 Sx
Bitemporal hemianopsia from b/l medial optic nerve compression
Hypotension from pre-existing ACTH deficiency
SAH sx
Cushing’s Disease (what it is & cause(s))
Endogenous overproduction from ACTH from ant pit
Caused by excessive endogenous or exogenous corticosteroids
Cushing’s Disease Sx (9)
Hypertension Truncal Obesity DM/gluc intolerance Menstrual irregularities Hirsutism Acne Purplish abd striae Thin skin/excessive bruising Proximal myopathy
Cushing’s Disease Dx Test
Dexamethasone suppression test
Tx after Dx of SAH
Cerebral angiography to identify aneurysm + best treatment
Most Common Location(s) of SAH Aneurysm (1 category, 3 example)
80-80% from anterior cerebral circulation:
A Comm, P Comm, or Trifurcation of MCA
Bacterial Meningitis Causative Agent (kids vs. adults)
Kids: Neisseria meningitidis
Adults: S. pneumo
Bacterial Meningitis Tx (3)
IV ampicillin, PCN G, and 3GCephalosporins (ceftriaxone, cefotaxime, ceftazidime)
Bacterial CSF (app/OP/WBC/Prot/Gluc)
App: Turbid OP: Elevated WBC: Very elevated, PMN predom Prot: Elevated Gluc: Low
Viral CSF (app/OP/WBC/Prot/Gluc)
App: Clear OP: Nml WBC: Slightly elevated, lymphocytic predominant Prot: Maybe mildly elevated Gluc: Nml
Fungal CSF (app/OP/WBC/Prot/Gluc)
App: Clear OP: Nml-Elevated WBC: Elevated Prot: Elevated Gluc: Nml-low
3 Causative Agents Newborn/Infant Meningitis
GBS
Listeria
E. Coli
Newborn/Infant Meningitis Tx
Ampicillin + gentamicin
NPH Imaging
Enlarged ventricles
Sydenham’s Chorea
Insidious chorea that can last over 6 months, often in girls; result of rheumatic fever
