Day 12

Question 1

Reflex Sympathetic Dystrophy

Answer 1

Injury then leads to crazy sympathetic response in the area, constant pain, and eventually tissue death

Question 2

Best Predictor for Future Violence

Answer 2

Past Violence

Question 3

Two CYPS induced by Carbamazepine

Answer 3

2C19 and 3A4

Question 4

Standard of Substituted Judgment

Answer 4

Surrogate decision maker makes decision based on what patient would have wanted

Question 5

Risperidone Metabolism

Answer 5

2D6 (so incr by a lot of meds, including some SSRIs like fluoxetine)

Question 6

Quinidine and Fluoxetine Shared Inhibition

Answer 6

2D6 Inhibitors

Question 7

Nuedexta

Answer 7

DXM + Quinidine for pseudobulbar affect

Question 8

FGA that’s lowered by smoking

Answer 8

Haloperidol, bc of smoking’s 1A2 inhibition

Question 9

Sheehan’s Syndrome (what it is)

Answer 9

Posterior pituitary infarction/apoplexy after birth

Question 10

Sheehan’s Syndrome 3 Sx

Answer 10

Bitemporal hemianopsia from b/l medial optic nerve compression
Hypotension from pre-existing ACTH deficiency
SAH sx

Question 11

Cushing’s Disease (what it is & cause(s))

Answer 11

Endogenous overproduction from ACTH from ant pit

Caused by excessive endogenous or exogenous corticosteroids

Question 12

Cushing’s Disease Sx (9)

Answer 12

Hypertension
Truncal Obesity
DM/gluc intolerance
Menstrual irregularities
Hirsutism
Acne
Purplish abd striae
Thin skin/excessive bruising
Proximal myopathy

Question 13

Cushing’s Disease Dx Test

Answer 13

Dexamethasone suppression test

Question 14

Tx after Dx of SAH

Answer 14

Cerebral angiography to identify aneurysm + best treatment

Question 15

Most Common Location(s) of SAH Aneurysm (1 category, 3 example)

Answer 15

80-80% from anterior cerebral circulation:

A Comm, P Comm, or Trifurcation of MCA

Question 16

Bacterial Meningitis Causative Agent (kids vs. adults)

Answer 16

Kids: Neisseria meningitidis
Adults: S. pneumo

Question 17

Bacterial Meningitis Tx (3)

Answer 17

IV ampicillin, PCN G, and 3GCephalosporins (ceftriaxone, cefotaxime, ceftazidime)

Question 18

Bacterial CSF (app/OP/WBC/Prot/Gluc)

Answer 18

App: Turbid
OP: Elevated
WBC: Very elevated, PMN predom
Prot: Elevated
Gluc: Low

Question 19

Viral CSF (app/OP/WBC/Prot/Gluc)

Answer 19

App: Clear
OP: Nml
WBC: Slightly elevated, lymphocytic predominant
Prot: Maybe mildly elevated
Gluc: Nml

Question 20

Fungal CSF (app/OP/WBC/Prot/Gluc)

Answer 20

App: Clear
OP: Nml-Elevated
WBC: Elevated
Prot: Elevated
Gluc: Nml-low

Question 21

3 Causative Agents Newborn/Infant Meningitis

Answer 21

GBS
Listeria
E. Coli

Question 22

Newborn/Infant Meningitis Tx

Answer 22

Ampicillin + gentamicin

Question 23

NPH Imaging

Answer 23

Enlarged ventricles

Question 24

Sydenham’s Chorea

Answer 24

Insidious chorea that can last over 6 months, often in girls; result of rheumatic fever

Question 25

BPAD Prevalence by Gender

Answer 25

No difference

Question 26

Amaurosis Fugax

Answer 26

Transient ipsilateral blindness from carotid insufficiency

Question 27

4 Pharm Tx of ET

Answer 27

1. Beta blockers (propranolol)
2. Primidone
3. Benzos
4. Botox

Question 28

TCAs in ET

Answer 28

Not effective & may worsen

Question 29

Schizophrenia Prevalence Urban vs. Rural

Answer 29

Urban higher (also higher in severity/morbidity)

Question 30

Schizophrenia Baby Birth Temporality

Answer 30

High in cases born in winter & early spring

Question 31

Friedrich’s Ataxia (inheritance pattern, mutation)

Answer 31

AR, trinucleotide rpt expansion (GAA) on Ch 9

Question 32

Friedrich’s Ataxia Onset and Progression

Answer 32

Adolescence, gait ataxia, loss of LE proprio + DTRs, and some other CNS/bulbar involvement. Eventually wheelchair bound

Question 33

Friedrich’s Ataxia Mortality

Answer 33

Die from hypertrophic cardiomyopathy in about 50% of cases, usually in 4th decade

Question 34

Myotonic Dystrophy Type I (inheritance pattern, what it is, etc)

Answer 34

AD trinucleotide rpt (CTG) on Ch 19