Day 13 Flashcards
Migraine Chromosome
19
Autism Chromosome
5
CNS Cystericercosis Tx
Albendazole (or praziquantel) + parenteral steroids
Echinococcosis
Larval tapeworms from dogs that cause solitary, non-edematous lesions. Surgical resection or albendazole if can’t
Leishmaniasis Organism Type
Protozoan
Leishmaniasis Neurologic Syndrome
Visceral sx accompanied by inflammatory neuropathy that can resemble GBS
Toxoplasmosis Organism Type & Source
Protozoan from migratory birds and cats
Toxoplasmosis Population
AIDS
Toxoplasmosis Imaging Presentation (vs. CNS Lymphoma)
Multifocal ring-enhancing lesions (vs. solitary lesion w/ subendymal spread)
Toxoplasmosis Tx
Pyrimethamine and sulfadizeine + folinic acid
EGT vs. CDT vs. GGT
EGT: Good for short term alcohol ingestion, rises quickly and wanes 24-36hrs
CDT: Good for long-term. Drink heavy for 2 weeks, stays for 30 days
GGT: High sensitivity but low specificity, even moderate will stick around for a few weeks.
Most Common Alcoholic Neuro Complication (& onset)
Alcohol neuropathy: 75% of alcoholics, mixed motor/sensory, symmetrically in feet and rises
Alcoholic Dementia Notable Deficits
Greater loss in fine motor and verbal fluency than in AD
Marchiafava-Bignami Ds
Rare demyelinating ds of corpus callosum in alcoholics
Miller-Fisher Syndrome
Variant of GBS with triad of gait ataxia, areflexia, and opthalmoplegia
Lewy Bodies Pathology
Diffuse throughout cortex, eosinophilic inclusions on hematoxylin + eosin stain
Konrad Lorenz (!) Development Concept
Imprinting (ducks following Nazi mom around)
He also obviously did aggression
Most Common Organism for Preceding GBS
Campylobacter jejuni (GI)
GBS Classic Nerve Conduction Studies (3)
Slowed conduction, loss of H reflex, prolonged F wave latencies
GBS CSF
Cytoalbuminologic Dissociation:
Elevated protein w/ acellular fluid
GBS Nerve Bx
Can have complement fixing Abs to myelin
Adenylyl Cyclase
Actually makes cAMP from ATP
