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Derm Pharm 2020 > CYP 450 > Flashcards

CYP 450 Flashcards

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Dermatology Board Prep flashcards
1
Q 
CYP-P450 Inhibitors (mainly CYP3A4):
A - Antifungals (Azoles, Allylamine Terbinafine) + Amiodarone + Antiparasitic (Albendazole, Thiabendazole)
O - Omeprazole
D - Disulfiram
E - Erythromycin + Estrogen
V - Valproate
I - Isoniazid
C - Cimetidine + Ciprofloxacin + Cephalosporins + Calcium Channel Blocker (Verapamil, Diltiazem)
E - Ethanol (acute)
S - Sulphonamides
A

Doxycycline
Diuretics
Fluoxetine (SSRI)
Grapefruit juice

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2
Q

CYP1A2 Inhibitor

A

Ciprofloxacin (Fluoroquinolones)
Albendazole (Antiparasitic)
Thiabendazole (Antiparasitic)

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3
Q

CYP2D6 Inhibitor

A

Terbinafine (Allylamine)

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4
Q 
CYP450 Inducers:
P - Phenytoin, Phenobarbital
C - Carbamazepine
B - Bexarotene (Retinoid) + Barbiturates
R - Rifampicin
A - Alcohol (chronic) + Antifungal (Griseofulvin)
S - Sulphonylureas + St Johns Wort
A

True

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5
Q

CYP3A4 Substrate

A 
CsA
Doxycycline
Lignocaine 
Ivermectin
Warfarin
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6
Q

CYP1A2 Substrate

A

Theophylline

Warfarin

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7
Q

CYP2C9 Substrate

A

Warfarin

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8
Q

CYP2D6 Substrate

A 
Beta blockers
TCA - Doxepine 
SSRIs
MAO inhibitors 
Antiarrhythmic agents
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Derm Pharm 2020 (47 decks)

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