3 - Topical Minoxidil Flashcards
Minoxidil is available as a 2% and 5% solution and 5% foam
True
Minoxidil increases the duration of the anagen growth phase and gradually enlarges miniaturised hair follicles (vellus hairs) into mature terminal hairs
True
Minoxidil is an ATP sensitive potassium channel opener
True
Vascular endothelial growth factor (VEGF) is a proposed promoter of hair growth stimulated by the adenosine signalling pathways
True (hence mode of action of minoxidil)
Minoxidil stimulates prostaglandins in the dermal papillae
True
Minoxidil is indicated for male pattern androgenetic alopecia of the vertex of the scalp
True
Minoxidil is most efficacious in the treatment of androgenetic alopecia affecting the crown area for up to 12 months
True
Twice daily minoxidil therapy should be continued indefinitely as patients who go on to daily maintenance therapy beginning at 12 months may have decreased hair counts
True
The 5% formulation is more superior than the 2% formulation in female pattern androgenetic alopecia
True
Minoxidil may cause irritant dermatitis
True
Minoxidil may cause allergic contact dermatitis
True
Minoxidil may cause hypertrichosis of skin other than the scalp if there is inadvertent application to that site
True
There is minimal systemic absorption of topical Minoxidil
True
Less inadvertent application and systemic absorption may be expected from the foam vehicle than the solution
True
Minoxidil is not recommended in pregnant and nursing women
True