3 - Topical Dithranol (Anthralin)

Question 1

Dithranol is also known as Anthralin

Answer 1

True

Question 2

Dithranol inhibits monocytes’ proinflammatory activity

Answer 2

True

Question 3

Dithranol induces extracellular generation of oxygen free radicals which induces irritation

Answer 3

True

Question 4

The irritation associated with Dithranol improves with repeated application due to tolerance

Answer 4

True

Question 5

Dithranol has anti-Langerhans cell effects

Answer 5

True

Question 6

Dithranol is approved for the use in chronic plaque psoriasis especially on localised plaques resistant to other therapies

Answer 6

True

Question 7

Dithranol has been combined with UVB phototherapy with good results

Answer 7

True

Question 8

Dithranol may cause staining of clothing, skin, hair and nails

Answer 8

True

Question 9

Dithranol causes an irritant contact dermatitis and a short contact treatment regimen is commonly used to overcome this adverse effect

Answer 9

True

Question 10

Dithranol is pregnancy category C and is not recommended in pregnant or nursing mothers

Answer 10

True