CVS - ANS Flashcards
What are the transmitters and receptors in the parasympathetic NS?
Long pre ganglionic neurone releases ACh to nicotonic receptors on the post ganglionic neurone.
This also releases ACh onto muscarinic receptors on the target tissue.
What are the transmitters and receptors of the sympathetic NS?
Short pre ganglionic neurone releases ACh to nicotonic receptors on the longer post ganglionic neurone
This releases noradrenaline to adrenoreceptors on the target tissue
What are the 4 types of adrenoreceptors (in SNS ovs)
a1
a2
B1
B2
What is the sympathetic nervous effect on the heart?
Increases rate and force of contraction
Which adrenoreceptor receives the SNS signal in the heart?
B1
What is the PS effect on the heart?
Reduces heart rate
What receptor recieves the PS signal in the heart?
M2
What is the S effect on the lungs
Relaxation
What adrenoreceptor receives the SNS signal in the lungs?
B2
What is the SNS effect on the pupil?
Dilation
What adrenoreceptor recieves the SNS signal in the pupil?
a1
What is the PS effect on the pupil?
Contraction
What receptor responds to the PNS in the pupil
M3
What is nerve responsible for PS control of the heart?
Vagus nerve
Which type of innervation dominates the heart at rest?
The parasympathetic NS
How does the SNS effect pacemaker potential?
B1 receptors are activated
Causing increased cAMP
More HCN activated
This speeds up PP (increasing the slope)
How does the PSNS affect pacemaker potential ?
M2 receptors increase K+ conductance and cAMP decreases
This decreases the pacemaker potential
How does the SNS increase the contractory force?
The noradrenaline increases contractory force by the increase cAMP activating PKA - this leads to phosphorylation of Ca2+ channels increasing calcium entry.
Where does the control of the CVS occur?
Medulla oblongata
Where does the medulla oblongata receive info from?
From barareceptors
