CVS - ANS Flashcards

0
Q

What are the transmitters and receptors in the parasympathetic NS?

A

Long pre ganglionic neurone releases ACh to nicotonic receptors on the post ganglionic neurone.
This also releases ACh onto muscarinic receptors on the target tissue.

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1
Q

What are the transmitters and receptors of the sympathetic NS?

A

Short pre ganglionic neurone releases ACh to nicotonic receptors on the longer post ganglionic neurone
This releases noradrenaline to adrenoreceptors on the target tissue

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2
Q

What are the 4 types of adrenoreceptors (in SNS ovs)

A

a1
a2
B1
B2

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3
Q

What is the sympathetic nervous effect on the heart?

A

Increases rate and force of contraction

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4
Q

Which adrenoreceptor receives the SNS signal in the heart?

A

B1

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5
Q

What is the PS effect on the heart?

A

Reduces heart rate

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6
Q

What receptor recieves the PS signal in the heart?

A

M2

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7
Q

What is the S effect on the lungs

A

Relaxation

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8
Q

What adrenoreceptor receives the SNS signal in the lungs?

A

B2

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9
Q

What is the SNS effect on the pupil?

A

Dilation

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10
Q

What adrenoreceptor recieves the SNS signal in the pupil?

A

a1

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11
Q

What is the PS effect on the pupil?

A

Contraction

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12
Q

What receptor responds to the PNS in the pupil

A

M3

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13
Q

What is nerve responsible for PS control of the heart?

A

Vagus nerve

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14
Q

Which type of innervation dominates the heart at rest?

A

The parasympathetic NS

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15
Q

How does the SNS effect pacemaker potential?

A

B1 receptors are activated
Causing increased cAMP
More HCN activated
This speeds up PP (increasing the slope)

16
Q

How does the PSNS affect pacemaker potential ?

A

M2 receptors increase K+ conductance and cAMP decreases

This decreases the pacemaker potential

17
Q

How does the SNS increase the contractory force?

A

The noradrenaline increases contractory force by the increase cAMP activating PKA - this leads to phosphorylation of Ca2+ channels increasing calcium entry.

18
Q

Where does the control of the CVS occur?

A

Medulla oblongata

19
Q

Where does the medulla oblongata receive info from?

A

From barareceptors