CSF Flashcards
CSF functions (3)
- Supply nutrients to the CNS
- Remove metabolic waste
- Produce a mechanical barrier to cushion the brain and spinal cord against trauma
Lines the brain and spinal cord and are composed of three layers
Meninges
An outer layer, lines the skull and vertebral canal
Dura mater
Spider-like, filamentous inner membrane
Arachnoid mater
Innermost layer, lines the surface of the brain and spinal cord
Pia mater
in between arachnoid mater and pia mater; where CSF flow
Subarachnoid space
specific part of the brain that produces CSF
Choroid Plexus
The choroid plexuses are capillary networks that form the CSF from plasma by mechanisms of selective filtration under ________ and _______
hydrostatic pressure and active transport secretion.
T/F. The chemical composition of the CSF does resemble an ultrafiltrate of plasma
FALSE. The chemical composition of the CSF does NOT resemble an ultrafiltrate of plasma
rate of CSF production
20 ml/hr
A tightly fitting junctures structure of endothelial cells in the choroid plexus;
Protects the brain from chemicals and other substances circulating in the blood that can harm the brain tissue
Blood-Brain Barrier
Disruption of BBB allows _____, _____ and other chemicals to enter CSF
WBC; protein
CSF Collection (2)
Lumbar puncture/tap and cisternal puncture
Pressure before CSF is collected
between 90 and 180 mmHg
Volume collected when CSF is normal.
20 mL of specimen may be removed
On closing, the pressure should be between ____ and ____
10 and 30 mmHg
A marked decrease in pressure following this procedure suggests __________________ or ____________
cerebellar herniation or spinal cord compression
If the CSF pressure is less than or greater than normal 90-180 mmHg, only _____ is used
1-2 ml