CHEMICAL ANALYSIS OF SPINAL FLUID CSF PROTEIN Flashcards
1
Q
Normal Values of CSF PROTEIN
A
Adults = 15-45 mg/dL
2
Q
CSF protein is increased in:
Damage to the BBB: (4)
Others: (10)
A
Damage to the BBB:
* Meningitis
* Hemorrhage
* Increase Antibody production
* Multiple sclerosis
Others:
* Uremia
* Diabetes
* Cushing disease
* CNS tumor
* Myxedema
* Polyneuritis
* Connective tissue disease
* Neurosyphilis
* Guillain Barre syndrome
3
Q
CSF Protein is decreased in (4)
A
CSF leakage/trauma, water intoxication, Rapid CSF production, Recent puncture
4
Q
Major CSF Protein
A
Albumin
5
Q
2nd most prevalent CSF protein
A
Pre albumin
6
Q
Alpha globulin
A
Haptoglobin, ceruloplasmin
7
Q
Beta-globulins
A
TAU protein: carbohydrate-deficient transferrin; found on CSF not in serum
8
Q
Gamma globulins
A
IgG and some IgA
