CELLS AND INCLUSIONS SEEN IN SYNOVIAL FLUID Flashcards

1
Q

Polymorphonuclear leukocyte

A

Neutrophil

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2
Q

Neutrophil SIGNIFICANCE

A

Bacterial sepsis, Crystal induced inflammation

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3
Q

Mononuclear leukocyte

A

Lymphocyte

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4
Q

Lymphocyte SIGNIFICANCE

A

Non-septic inflammation

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5
Q

Large mononuclear leukocyte, may be vacuolated

A

Macrophage

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6
Q

Similar to macrophage, but may be multinucleated resembling a mesothelial cell

A

Synovial lining cell

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7
Q

Neutrophil containing characteristic ingested “Round homogenous body”

A

LE cell

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8
Q

LE cell significance

A

Lupus erythematosus

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9
Q

Vacuolated macrophage with ingested neutrophils

A

Reiter cell

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10
Q

Reiter cell significance

A

Reiter syndrome
Non-specific inflammation

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11
Q

Neutrophil with dark cytoplasmic granules containing immune complexes

A

RA cell
(Ragocyte)

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12
Q

RA cell (Ragocyte) significance

A

Rheumatoid arthritis
Immunologic inflammation

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13
Q

Large multinucleated cells

A

Cartilage cells

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14
Q

Cartilage cells significance

A

Osteoarthritis

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15
Q

Macroscopically resembles polished rice
Microscopically shows collagen and fibrin
They are fragments of degenerating proliferative synovial cells or microinfarcted synovium

A

Rice bodies

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15
Q

Rice bodies significance

A

Tuberculosis, septic and rheumatoid arthritis

16
Q

Refractile intracellular and extracellular globules stain with Sudan

A

Fat droplets

17
Q

Fat droplets significance

A

Traumatic injury

18
Q

RBCs normal value for synovial fluid

A

<2000/ul

19
Q

WBCs normal value for synovial fluid

A

< 200 / ul

20
Q

Percentage for synovial fluid
Monocyte and macrophages %
Neutrophils
Lymphocytes

A

Monocyte and macrophages 65 %
Neutrophils <25 %
Lymphocytes <15 %

21
Q

An eosinophil of greater than 2 %is associated with allergic disease with

A

arthritis, hemorrhagic joint effusion, Lyme disease, parasitic arthritis, RA, and tubercular arthritis