Credit 6

Question 1

Most common malignant tumor of the kidney

Answer 1

1- Renal cell carcinoma
2- Nephroblastoma (Wilms tumor)
3- Primary tumors of the calyces and pelvis

Question 2

Oncocytoma

Answer 2

Benign from the intercallated cells of collecting ducts
10 % of renal tumors
Genetic : chrom 1, 14, Y
Histo : plethora of mitochondria tan color, fine granular eosinophilic cytoplasm
Central stellate scar
Removed by nephrectomy (avoid bleeding)

Question 3

Benign prostatic hyperplasia

Answer 3

90% men by 80 y
Dihydrotestosterone + 3 alpha androstanediol and increases in estrogen levels

Central and transitional region

Clinical symptoms : 10% of men
Lower urinary tract obstruction
Some -> complete obstruction -> painful distention of bladder and hydronephrosis

Increase of UTIs

Question 4

Prostatic adenocarcinoma

Answer 4

Most common cancer in males
And 2nd death
65-75 y
More than 50% when over 80 y

Question 5

Location of prostatic adenocarcinoma

Answer 5

Peripheral zone of the gland in a posterior location (70-80%)

Question 6

Nephretic syndrome

Answer 6

Hematuria
Oliguria, azotemia
Hypertension

Question 7

Nephrotic syndrome

Answer 7

Massive proteinuria
Hypoalbuminemia
Generalized edema
Hyperlipidemia lipiduria

Question 8

Most frequent cause of nephrotic syndrome in children

Answer 8

Minimal change disease (lipoid nephrosis)

Question 9

Cystine renal calculi

Answer 9

1% of stones in chilhood hereditary cystinuria

Question 10

Calcium 75%

Answer 10

Calcium oxalate

Question 11

Fibroadenoma

Answer 11

Benign biphasic tumor with epithelial and mesenchymal stromal

Under 30 y

Question 12

Most common in situ breast carcinom

Answer 12

Ductal carcinoma

Question 13

Most common invasive breast carcinoma

Answer 13

Carcinoma no special type

Question 14

Invasive ductal carcinoma NST

Answer 14

In 80% of cases foci
Grading : tubule/gland formation
Nuclear pleomorphism
Mitotic count

Significantassociation bet histological grade and survival

Method by bloom

Question 15

Paget disease of nipple

Answer 15

Presence of malign cells within the squamous epithelium almost always associated with intraductal carcinoma

Question 16

Paget disease prognosis

Answer 16

Dependent on the presence pr absence of underlying invasive carcinoma in the deep breast tissue

Question 17

Sarcoma botryoides

Answer 17

Embryonal rhabdomyosarcoma
Rare form if primary vaginal cancer - polypoid masses
In children <5y
May occur in other sites like urinary bladder and bile duct

Question 18

Berger disease

Answer 18

Iga nephropathy

Question 19

Alport syndrome

Answer 19

X linked hereditary nephritis

Question 20

Buerger disease

Answer 20

Thromboangitia obliterans

Question 21

Call Exner bodies are characteristics of

Answer 21

Granulosa cell tumor

Question 22

Kimmelstiel-Wilson nodules typically occurs

Answer 22

Diabetic glomerulosclerosis

Question 23

Produce ascites and hydrothorax

Answer 23

Thecoma fibroma

Question 24

Call exner bodies

Answer 24

Granulosa theca cells