CPT1: CNS Flashcards

1
Q

Describe the Nervous system

HInt: think what it is made up of

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the purpose of the thalamus?

A

Intigration and relay of sensory information to the cerebral cortex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the purpose of the midbrain

A

Relays ascending/ descending inerve signals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the purpose of the Cerebrum

A
  • sets intellegance
  • memory
  • learning
  • sensory perception
  • initiation of movement
  • reasoning
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the function of the basal nucleus?

A

Muscle tone and fine coordination of movement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the function of the hypothalamus

A
  • hormone out put
  • autonomic control
  • thirst, appetite
  • emotion
  • sex
  • rhyth,

Ashtma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the function of the PONS?

A

bridge between both hemispheres of the cortex, relays info from cranial nerves

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the function of the medulla oblongata?

A

relays sensory info from spinal cord, CVS centre and respiratory

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the 3 components which make up the cortical motor system?

A
  1. Primary motor cortex
  2. Pre-motor cortex
  3. posterial parietal cortex
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the primary motor cortex responsible for?

A

Excution of movement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the pre-motor cortex responsible for?

A

Movement planning/ sequence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the posterial parietal motor cortex responsible for?

A

sensoty guidance of movement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Describe the differences in pryamidal and extrapyramidal motor systems

A
  1. Pyramidal controls volunatry movemenets and is faster. It has high speed connections to lower motor neurons which passes to striated muscles
  2. Extrapryamidal motor system controls involuntary actions and postual actions. These are slower but just as effective
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Describe the extrapyramidal and pyramidal motor systems

A
  1. pyramidal - Nerve connection from mortor cortex directly to lower motor neurons. These are passed to spinal cord and brain stem then to striated muscle
  2. Extrapyramidal - nerve connections from MC to basal ganglia+ brain stem centres. This is then passed to lower motor neurons then BS and SC and then striated muscle
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Give examples of CNS neruonal GLIAL cells

A
  • oligodendrocytes
  • astrocytes
  • microglia
  • ependymal
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are examples of CNS neuronal vascular cells?

A
  • endothelium
  • pericytes
  • smooth muscle
17
Q

Describe glutamate up take/ metabolism/ release

A
  1. In astrocyte glutamate converted to glutamine by glutamine synthase
  2. Glutamine trasnported by glutamine trasporter to neuron
  3. in neuron glutaminase metabolises it to glutamat which is packaged into vesicles and released into the synapses
18
Q

What are potiental drug targets in the CNS?

A
  • Receptors
  • Transmitter release
  • Transmitter synthesis
  • Transmitter re-uptake ( transporters)
  • Glial cell function
  • Blood flow