Cough and Colds preparation

Question 1

Nasal decongestants are vaso______.

Answer 1

vasoconstrictor

Adrenergic agonist

Question 2

Topical decongestants, short-acting

Answer 2

Phenylephrine

Question 3

Topical decongestants, intermediate acting

Answer 3

Naphazoline

Tetrahydrozoline

Question 4

Topical decongestants, long acting

Answer 4

Oxymetazoline

Xylometazoline

Question 5

Decongestants should not exceed 3-5 days because of risk of

Answer 5

Rhinitis medicamentosa

Question 6

Systemic decongestants (3Ps)

Answer 6

Pseudoephedrine
Phenylpropanolamine
Phenylephrine

Question 7

Systemic decongestants ADR

Answer 7

Hypertension

Question 8

Centrally acting anti-tussive (4)

Answer 8

Dextrometorphan
Codeine
Noscapine
Butamirate

Question 9

MOA of centrally acting anti-tussive

Answer 9

Inc. threshold for cough in the medulla

Question 10

MOA of peripherally acting

Answer 10

Dec. sensitivity of the peripheral irritants receptors

Question 11

Peripheral acting anti-tussive

Answer 11

Levodropropizine

Benzonatate

Question 12

MOA of expectorants

Answer 12

Inc. the amount of respiratory tract fluid

Question 13

Example of Expectorants

Answer 13

Guiafenesin

Question 14

MOA of mucolytic

Answer 14

Break disulfide linkages between mucus

Question 15

Examples of Mucolytic

Answer 15

N-acetylcysteine (NAC)

stimulates also glutathione for paracetamol toxicity

Question 16

Toxic metabolite of Acetaminophen

Answer 16

NAPQI

Question 17

Mucoregulators (3)

Answer 17

Ambroxol
Bromhexine
Carbocisteine

Question 18

Mucoregulator MOA

Answer 18

1. Break disulfide linkages

2. Enhance mucociliary action