Anti-Malaria

Question 1

Tx: Chloroquine-SENSITIVE P. falciparum

Answer 1

Chloroquine

Question 2

Tx: P. vivax and P. ovale

Answer 2

Chloroquine then Primaquine

Question 3

Tx: Uncomplicated Chloroquine-resistant P. falciparum

Answer 3

Artemether + Lumefantrine (Co-Artem)

Question 4

Tx: Severe or Complicated P. falciparum

Answer 4

Artesunate then Doxycycline/ Clindamycin/ Co-Artem

Question 5

Tissue Schizonts

Answer 5

Primaquine

Atovaquone

Question 6

Gametocide

Answer 6

Primaquine

Question 7

Sporonticide

Answer 7

proguanil

pyrimethamine

Question 8

The common structural form of anti-malarial agents

Answer 8

Quinoline Ring
Acridine Ring (Quinoline + benzene)

Question 9

Malignant tertian malaria

Answer 9

Plasmodium falciparum

Question 10

Benign tertian malaria (more common)

Answer 10

Plasmodium vivax

Question 11

DOC for Pregnant

Answer 11

Quinine

Question 12

DOC for erythrocytic malaria

Answer 12

Chloroquine

Question 13

WOF Chloroquine?

Answer 13

QT Prolongation

Question 14

Only drug effective against exoerythrocytic stages

Answer 14

Primaquine

Question 15

Tx: Effective single agent for suppressing and curing multi-drug resistant forms of P. falciparum

Answer 15

Mefloquine

Question 16

Gametocidal against vivax and ovale

Answer 16

Quinidine
Chloroquine

Q.C.

Question 17

Gametocidal against ALL

Answer 17

Primaquine
Artemisin

PrimaArt

Question 18

Prevention of relapse?

Answer 18

Primaquine

Question 19

Radical cure of v,o?

Answer 19

Primaquine

Question 20

Pvnt: Areas w/o resistant P. falciparum

Answer 20

Chloroquine

Question 21

Pvnt: Areas WITH chloroquine-resistant P. falciparum

Answer 21

Atovaquone - proguanil

Mefloquine

Question 22

Pvnt: Areas with multi-drug resistant P. falciparum

Answer 22

Doxycycline

100mg daily 2 days before travel continued for 4 weeks after leaving the area