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Pharmacology > Anti-Malaria > Flashcards

Anti-Malaria Flashcards

1
Q

Tx: Chloroquine-SENSITIVE P. falciparum

A

Chloroquine

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2
Q

Tx: P. vivax and P. ovale

A

Chloroquine then Primaquine

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3
Q

Tx: Uncomplicated Chloroquine-resistant P. falciparum

A

Artemether + Lumefantrine (Co-Artem)

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4
Q

Tx: Severe or Complicated P. falciparum

A

Artesunate then Doxycycline/ Clindamycin/ Co-Artem

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5
Q

Tissue Schizonts

A

Primaquine

Atovaquone

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6
Q

Gametocide

A

Primaquine

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7
Q

Sporonticide

A

proguanil

pyrimethamine

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8
Q

The common structural form of anti-malarial agents

A 
Quinoline Ring
Acridine Ring (Quinoline + benzene)
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9
Q

Malignant tertian malaria

A

Plasmodium falciparum

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10
Q

Benign tertian malaria (more common)

A

Plasmodium vivax

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11
Q

DOC for Pregnant

A

Quinine

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12
Q

DOC for erythrocytic malaria

A

Chloroquine

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13
Q

WOF Chloroquine?

A

QT Prolongation

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14
Q

Only drug effective against exoerythrocytic stages

A

Primaquine

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15
Q

Tx: Effective single agent for suppressing and curing multi-drug resistant forms of P. falciparum

A

Mefloquine

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16
Q

Gametocidal against vivax and ovale

A

Quinidine
Chloroquine

Q.C.

17
Q

Gametocidal against ALL

A

Primaquine
Artemisin

PrimaArt

18
Q

Prevention of relapse?

A

Primaquine

19
Q

Radical cure of v,o?

A

Primaquine

20
Q

Pvnt: Areas w/o resistant P. falciparum

A

Chloroquine

21
Q

Pvnt: Areas WITH chloroquine-resistant P. falciparum

A

Atovaquone - proguanil

Mefloquine

22
Q

Pvnt: Areas with multi-drug resistant P. falciparum

A

Doxycycline

100mg daily 2 days before travel continued for 4 weeks after leaving the area

Pharmacology (13 decks)

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