Anti-protozoal/ Anti-helmintic Flashcards

1
Q

MOA: Tubulin binding and cellular disruption

A

Benzimidazoles

Ex. Albendazole, Mebendazole

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2
Q

MOA: GABA Agonists

A

Piperazines

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3
Q

MOA: GluCl- potentiators

A

Ivermectin

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4
Q

MOA: Enhance Ca++ permeability

A

Praziquantel

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5
Q

DOC: Roundworm (Ascaris lumbricoides)
DOC: Hookworms (Ancylostoma duodenale, Necator Americanus)
DOC: Pinworm (Enterobius vermicularis)

A

Mebendazole, Albendazole, Pyrantel

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6
Q

DOC: Threadworm (Strongyloides stercoralis)

A

Ivermectin

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7
Q

DOC: Whipworm (Trichuris trichiura)

A

Mebendazole

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8
Q

DOC: Whipworm (Trichinella spiralis)

A

Albendazole

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9
Q

DOC: Filiariasis

A

Diethyl carbamazine

Ivermectin

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10
Q

DOC: Tapeworms (Taenias & hymenolepis)

A

Praziquantel

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11
Q

DOC: Hydatid disease

A

Albendazole

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12
Q

DOC: Asymptomatic intestinal ameobic infections

A

Diloxanide furoate

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13
Q

MOA: Inhibits protein synthesis

A

Paramomycin

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14
Q

DOC: Early stage of west african trypanosomiasis
ALT: Tx for visceral leishmaniasis and pneumocytosis

A

Pentamine

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15
Q

DOC: African trypanosomiasis

A

Suramin

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16
Q

1st line for cutaneous and visceral leishmaniasis

A

Sodium stibogluconate

17
Q

DOC: Acute american trypanosomiasis (Chaga’s disease)

A

Nifurtimox

18
Q

Used w/ metronidazole in the Tx of intestinal and extrainstestinal ameobic infections

A

Iodoquinol

Paromycin