Corticol Organisation And Function Flashcards

1
Q

what is the cerebral cortex and where is it found?

A

Surface of brain covers it all

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2
Q

Organisation of cerebral cortex

A

organised into lobes → frontal, temporal x2, parietal x2, occipital
Further organized unto cortical layers and columns

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3
Q

What are folds called

A

gyri (ridges) and sulci (grooves)

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4
Q

define cytoarchitecture?

A

e.g. cell size, spacing/packing density and layering

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5
Q

Frontal lobe

A

regulate + initiate motor function

language

cognitive functions e.g. planning

memory

attention

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6
Q

Parietal lobe

A

Sensation
Sensory aspects of language
Spatial orientation
Self perception

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7
Q

Occipital and temporal lobe

A

Visual info
Temporal-hearing emotions and memory

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8
Q

what does the limbic lobe include?

A

amygdala, hippocampus, cingulate gyrus, mamillary body

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9
Q

What’s Limbic lobe concerned with

A

Memory
Emotion
Motivation
Learning

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10
Q

Insular cortex

A

In lateral fissure
Concerned with visceral sensation autonomic control and interoreception

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11
Q

grey matter vs white matter → what is each made of, which is the outer layer?

A

grey matter on the outside

grey = neuronal cell bodies, glial cells

white = myelinated axons arranged in tracts

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12
Q

three types of white matter tracts?

A
  • association fibresconnect areas in the same hemisphere
  • commissural fibresconnect homologous structures in opposite hemispheres
  • projection fibresconnect cortex with lower brain structures
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13
Q

association fibres split into which categories?

A

Short and long fibres

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14
Q

main association fibres → what do they connect?

A
  • superior longitudinal fasciculusfrontal ↔ occipital
  • arcuate fasciculusfrontal ↔ temporal
  • inferior longitudinal fasciculustemporal ↔ occipital
  • uncinate fasciculus (under arcuate and shorter)anterior frontal ↔ temporal
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15
Q

main commissural fibres?

A

corpus callosum

anterior commissure

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16
Q

two types of projection fibres for projection

A

afferent (towards cortex) and efferent (away from cortex)

  • internal capsule → between thalamus and basal ganglia
17
Q

where do projection fibres converge?

A

internal capsule → between thalamus and basal ganglia

18
Q

difference between primary and secondary/association cortices?

A

predictable vs less predictable function

topographical organisation present vs absent

left-right symmetry present vs weak/absent

  • premotor area (more lateral) and supplementary area (more medial) → both anterior
19
Q

association cortices for frontal lobe

A

premotor area (more lateral) and supplementary area (more medial) → both anterior

20
Q

what are these three involved in?frontal

A

primary controls fine voluntary movement, provides descending signals to execute these

supplementary area involved in planning internally cued complex movements

pre-motor area involved in planning externally cued complex movements

21
Q

where is the primary somatosensory cortex and what is its secondary cortex?

A

found posterior to central sulcus → postcentral gyrus, posterior to that is somatosensory association

22
Q

difference in function between these two? Parietal

A

primary processes somatic sensations from receptors eg fine touch vibration two point discrimination proprioreception and pain and temp
Somatosensory association interorets significance of sensory info e.g. recognising object in hand, awareness of self and personal space

23
Q

occipital lobe → primary visual vs visual association functions?

A

primary processes visual stimuli, visual association gives meaning and interpretation

24
Q

temporal lobe → primary auditory vs auditory association functions?

A

processes stimuli / gives meaning and interpretation

25
Q

main other association areas?

A

prefrontal cortex, Broca’s area, Wernicke’s area

26
Q

difference between Broca and Wernicke?

A

Broca = production of language, Wernicke = understanding of language

lesions cause expressive aphasia / receptive aphasia

27
Q

function after lesion impairment → examples?

A
  • frontalbehavioural change
  • parietalcontralateral neglect, lack of awareness of self/personal space on one side
  • temporalloss of ability to form new memories, recognise stuff
  • occipitalblindness for primary / deficits in interpretation for association e.g. prosopagnosia → inability to recognise faces

Broca’s area
Expressive aphasia poor production of speech

Wernickes
Receptive aphasia poor comprehension of speech production is fine

28
Q

what does a PET scan show?

A

positron emission tomography → blood flow directly to a brain region

29
Q

what does an fMRI scan show?

A

functional magnetic resonance imaging → amount of blood oxygen in a brain region

30
Q

what do MEG and EEGs show?

A

magnetoencephalography & electroencephalography → event-related magnetic/electrical potentials

31
Q

what is TMS and what does it do?

A

transcranial magnetic stimulation → helps stimulate the brain and assess functional integrity of circuits, investigate function of a brain area

32
Q

what is tDCS?

A

transcranial direct current stimulation → direct current over the scalp to increase/decrease neuronal firing rates

33
Q

what is DTI and what is it useful for?

A

diffusion tensor imaging → assess structure based on diffusion of water molecules

34
Q

Prefrontal cortex

A

Attention
Adjusting social behaviour
Planning
Personality expression
Decision making

35
Q

DTI with tractography

A

3D recronstruction to assess neural tracts