Corrections - GI pt. 2 Flashcards
What does an AXR show in gallstone ileus?
SBO and air in the biliary tree
What happens in gallstone ileus?
A gallstone enters the small intestine where it lodges in the ileocaecal valve.
This is usually on a background of chronic cholecystitis.
What tool is used to screen patients for malnutrition?
The Malnutrition Universal Screening Tool (MUST)
What is the most common organism found on ascitic fluid culture in spontaneous bacterial peritonitis?
E. coli
What triad of features is seen in spontaneous bacterial peritonitis (SBP)?
1) ascites
2) abdo pain
3) fever
How is a diagnosis of SBP made?
Paracentesis –> neutrophil count >250 cells/ul
Who is SBP usually seen in?
Ascites 2ary to liver cirrhosis
What is given in the acute management of a variceal haemorrhage?
1) terlipressin
2) prophylactic IV Abx
Both should be given before endoscopy.
What is given for the prophylaxis of a variceal haemorrhage?
Propanolol & endoscopic variceal band ligation (EVL)
What is melanosis coli?
A condition characterised by the presence of pigment-laden macrophages in the lamina propria of the colon.
What is melanosis coli most commonly associated with?
Chronic use or abuse of anthraquinone-containing laxatives e.g. senna
What is the only test recommended for H. pylori post-eradication therapy?
Urea breath test
What is hepatorenal syndrome?
A type of functional kidney impairment that occurs in patients with advanced liver disease.
What are the 3 key features of hepatorenal syndrome?
1) ascites
2) low urine output
3) significant increase in serum creatinine
What is recommended first line for hepatorenal syndrome?
Terlipressin (a vasopressin analogue)
Role of terlipressin in hepatorenal syndrome?
It works by inducing splanchnic vasoconstriction which reduces portal pressure and improves renal blood flow.
What triad of symptoms is seen in Boerhaave syndrome?
1) vomiting/retching
2) severe retrosternal chest pain typically radiating to the back
3) subcutaneous emphysema
What is Boerhaave syndrome?
Transmural oesophageal perforation secondary to an episode of forceful emesis.
When should PPIs be stopped before an upper GI endoscopy?
2 weeks before
Why should PPIs be stopped 2 weeks before an endoscopy?
PPIs can reduce the size of ulcerative gastro-oesophageal malignancy, which can make them unidentifiable during endoscopic examination.
In B12 and folate deficiency, replacement of which takes priority?
Vitamin B12 replacement should always occur prior to folate replacement as folate replacement prior to B12 can precipitate subacute combined degeneration of the spinal cord.
What condition does the combination of deranged LFTs combined with secondary amenorrhoea in a young female strongly suggest?
Autoimmune hepatitis
Crypt abscess & goblet cells in UC vs Crohn’s?
UC:
- crypt abscesses seen (neutrophils migrate through the walls of glands to form crypt abscesses)
- depletion of goblet cells
Crohn’s:
- increased goblet cells
What is a long history of watery green diarrhoea post cholecystectomy caused by?
Bile-acid malabsorption –> this can be idiopathic, or seen in patient’s with Crohn’s disease.