Cardiology: Heart Block Flashcards
What is atrioventricular (AV) block (heart block)?
The partial or complete interruption of impulse transmission from the atria to the ventricles.
What is the most common cause of AV block?
Idiopathic fibrosis & sclerosis of the conduction system.
What investigations are required in all patients presenting with AV block?
1) ECG: to help determine the subtype of AV block
2) Labs (e.g. FBC, U&Es, TSH, troponin): to rule out underlying causes
3) Echocardiogram: to rule out structural heart disease
What are the 4 subtypes of AV block?
1) First-degree AV block
2) Second-degree AV block (type 1)
3) Second-degree AV block (type 2)
4) Third-degree (complete) AV block
What does first degree AV block involve?
The consistent prolongation of the PR interval (defined as >0.2 seonds) due to delayed conduction via the AV node.
What PR interval defines 1st degree heart block?
> 0.2 seconds i.e. >5 small squares
What is the PR inverval on an ECG?
The PR interval represents the time between atrial depolarisation and ventricular depolarisation.
From the beginning of the P wave to the beginning of the QRS interval.
What is every P wave is followed by in 1st degree heart block?
A QRS complex (i.e. there are no dropped QRS complexes, unlike some other forms of AV block).
What are some causes of 1st degree heart block?
First-degree AV block is common and can often be an incidental finding.
1) Enhanced vagal tone: often seen in athletes (non-pathological)
2) Post myocardial infarction
3) Lyme disease
4) SLE
5) Congenital
6) Myocarditis
7) Electrolyte derangements
8) Drugs: particularly AV blocking drugs such as beta-blockers, rate-limiting calcium-channel blockers, digoxin and magnesium
9) Thyroid dysfunction
Who can first degree AV block often be seen in?
Athletes (non pathological)
ECG findings in 1st degree AV block?
1) rhythm: regular
2) P wave: every P wave is present and followed by a QRS complex
3) PR interval: prolonged >0.2 seconds (5 small squares)
4) QRS complex: normal morphology and duration (<0.12 seconds)
Typical history & exam findings in 1st degree heart block?
Patients are usually asymptomatic.
Clinical examination is normally unremarkable.
What drugs can cause 1st degree heart block?
AV blocking drugs:
1) beta blockers
2) rate limiting calcium channel blockers e.g. diltiazem, verapamil
3) digoxin
4) magnesium
Complications of 1st degree heart block?
First-degree AV block does not usually progress to higher grade AV blocks.
Those with first-degree AV block may be at an increased risk of atrial fibrillation.
What are the 2 types of 2nd degree heart block?
1) Type 1: Mobitz type 1 AV block or Wenckebach phenomenon.
2) Type 2: Mobitz type 2 AV block.
What occurs in Mobitz type 1 AV block?
There is progressive prolongation of the PR interval until eventually the atrial impulse is not conducted, and the QRS complex is dropped.
AV nodal conduction resumes with the next beat and the sequence of progressive PR interval prolongation and the eventual dropping of a QRS complex repeats itself.
Who is second-degree AV block (type 1) often seen in?
Often seen in athletes (non-pathological)
Causes of second-degree AV block (type 1)?
1) Increased vagal tone: often seen in athletes (non-pathological)
2) Drugs: beta-blockers, calcium channel blockers, digoxin, amiodarone
3) Inferior myocardial infarction
4) Myocarditis
5) Cardiac surgery (mitral valve repair, Tetralogy of Fallot repair)
What type of MI can cause econd-degree AV block (type 1)?
Inferior MI - as the RCA supplies the AV node.
ECG findings in second-degree AV block (type 1)?
1) Rhythm: irregular
2) P wave: every P wave is present, but not all are followed by a QRS complex
3) PR interval: progressively lengthens before a QRS complex is dropped
4) QRS complex: normal morphology and duration (<0.12 seconds), but are occasionally dropped
Clinical features & exam findings in patients with second-degree AV block (type 1)?
History:
- Usually asymptomatic
- Some can develop symptomatic bradycardia and present with symptoms such as pre-syncope and syncope.
Exam:
- Irregular pulse
- Bradycardia
Complications of second-degree AV block (type 1)?
The patient may become haemodynamically compromised, although this is rare.
Management osecond-degree AV block (type 1)?
Usually, no intervention is required if the patient is asymptomatic. If the patient is symptomatic a pacemaker may be considered.
What happens in second-degree AV block (type 2) (Mobitz type 2 AV block)?
There is a consistent PR interval duration with intermittently dropped QRS complexes due to a failure of conduction.
The intermittent dropping of the QRS complexes typically follows a repeating cycle of every 3rd (3:1 block) or 4th (4:1 block) P wave.
Cause of second-degree AV block (type 2)?
Mobitz type 2 AV block is always pathological:
1) MI
2) Idiopathic fibrosis of the conducting system (Lenegre’s or Lev’s disease)
3) Cardiac surgery (especially surgery occurring close to the septum such as mitral valve repair)
4) Inflammatory conditions (rheumatic fever, myocarditis, Lyme disease)
5) Autoimmune (SLE, systemic sclerosis)
6) Infiltrative myocardial disease (amyloidosis, haemochromatosis, sarcoidosis)
7) Hyperkalaemia
8) Drugs (e.g. beta-blockers, calcium channel blockers, digoxin, amiodarone)
9) Thyroid dysfunction
Where does the block typically occur in 2nd degree AV block (type 2)?
1) Bundle branches (80%)
2) Bundle of His (20%)
PR interval in second degree heart block type 1 and 2?
Type 1: progressive prolongation of the PR interval until a dropped beat occurs
Type 2: PR interval is constant but the P wave is often not followed by a QRS complex
ECG findings in second-degree AV (type 2)?
1) Rhythm: irregular (may be regularly irregular in 3:1 or 4:1 block)
2) P wave: present but there are more P waves than QRS complexes
3) PR interval: consistent normal PR interval duration with intermittently dropped QRS complexes
4) QRS complex: normal (<0.12 seconds) or broad (>0.12 seconds)