Corrections - Cellulitis & NF

Question 1

What is the most common preexisting medical condition in patients with NF?

Answer 1

Diabetes

Question 2

What diabetic drug is a particular risk factor for NF? Why?

Answer 2

SGLT-2 inhibitors - increases urinary excretion of glucose, increasing the chances of developing a urinary and genital infection, including NF.

Question 3

What is the most commonly affected site in NF?

Answer 3

Perineum (Fournier’s gangrene)

Question 4

Risk factors for NF?

Answer 4

1) skin factors: recent trauma, burns or soft tissue infections

2) diabetes mellitus

3) IVDU

4) immunsuppression

Question 5

How can chickenpox result in NF or cellulitis?

Answer 5

Cellulitis –> From 2ary bacterial infection of the lesions.

NF –> Invasive group A streptococcal soft tissue infections may occur resulting in NF

Question 6

What increases the risk of 2ary bacterial infection of the lesions in chickenpox (and therefore increased risk of NF and cellulitis)?

Answer 6

NSAIDs

Question 7

Why do patients with orbital cellulitis require admission to hospital for IV antibiotics?

Answer 7

Due to risk of cavernous sinus thrombosis and intracranial spread

Question 8

What can increase the risk of necrotising fasciitis in patients with chicken pox?

Answer 8

NSAIDs

Question 9

What is the Abx of choice for cellulitis in pregnancy if the patient is penicillin allergic?

Answer 9

Erythromycin

Question 10

Is erythromycin or clarithromycin safer in pregnancy?

Answer 10

Erythromycin