Anaesthetics: Pre-Operative Assessment Flashcards

1
Q

What is the American Society of Anaesthetist (ASA) Scoring System?

A

Used routinely as part of the WHO Safer Surgery Checklist.

A grading system to determine the health of a person before a surgical procedure that requires anesthesia.

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2
Q

Described stages 1-6 of the ASA

A

1 - Normal health patient

2 - Mild systemic disease (e.g. asthma)

3 - Severe systemic disease

4 - Severe systemic disease that is a constant threat to life

5 - Moribumd patient, not expected to survive without the operation

6 - Declared brain-dead patient, organ removal for donor purposes

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3
Q

Give brief structure of anaesthetic pre-operative assessment

A

1) Previous anaesthetics

2) Allergies & intolerances

3) Medication history

4) Presenting complaint

5) PMH

6) Fasting period

7) Airway assessment

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4
Q

What are some key questions to ask about previous anaesthetics in the pre-operative assessment (POA)?

A

1) Has the patient had any previous anaesthetics? If so, was that under general anaesthetic or another method? – e.g. peripheral nerve blocks, spinal, epidural and/or sedation

2) Did they have any problems with previous anaesthetics?

3) Serious anaesthetic complications:
- malignant hyperthermia
- suxamethonium apnoea
- anaphylaxis
- difficult airway

4) Did they experience postoperative nausea and vomiting previously?

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5
Q

What is malignant hyperthermia?

A

A rare reaction to volatile anaesthetic agents and neuromuscular blocking drugs that can cause dangerously high body temperature and muscle contractions.

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6
Q

What is suxamethonium apnoea?

A

A deficiency in enzymes required to break down suxamethonium, resulting in prolonged paralysis of skeletal muscle.

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7
Q

During POA, if a patient says something like “Oh I was slow to wake up”, what should you ask?

A

Important to determine how seriously they were affected:

1) How long did they take to wake up? Was it a few hours or a few days?

2) Did they require intensive treatment unit (ITU) admission post-op due to problems waking up?

3) Is there any family history of problems with anaesthetics?

4) Have they or their family members had any specific testing? – i.e. genetic, allergy or other testing relating to anaesthetic agents (MH or suxamethonium apnoea)

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8
Q

How can you help to distinguish between an allergy and an intolerance?

A

Ask what kind of reaction they had to each medication e.g. rash, swelling, anaphylaxis, nausea/diarrhoea

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9
Q

What should you SPECIFICALLY ask about when discussing allergies & intolerances in POA?

A

Penicillin & NSAIDs

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10
Q

What should you SPECIFICALLY ask about when discussing medication history in POA?

A

1) anticoagulants

2) antiplatelets

3) antihypertensives

4) analgesics & when they last took them

5) “over the counter” and herbal medications.

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11
Q

Key questions to ask when discussing PMH in POA?

A

1) Who manages their chronic condition?

2) Recent GP visits and hospital admissions relating to a chronic condition

3) Recent changes in treatment

4) Associated complications of condition and body systems affected

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12
Q

Example questions to ask about asthma/COPD when discussing PMH in POA:

A

1) Regular medications, compliance and degree of control

2) Recent oral steroid treatment

3) Exacerbating factors

4) Smoking status

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13
Q

Example questions to ask about diabetes when discussing PMH in POA:

A

1) How is it controlled? Diet, oral medication or insulin?

2) How often do they check their capillary blood glucose and what’s normal for them?

3) Do they still have hypo-awareness?

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14
Q

How can a history of GORD affect anaesthetics?

A

Significant reflux would require rapid sequence induction and intubation to reduce the risk of stomach contents contaminating the airway.

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15
Q

Questions to ask about GORD in POA?

A

1) Triggers – e.g. food, lying supine

2) Associated symptoms – discomfort, acid into throat/mouth

3) Frequency and the most recent episode

4) How is it controlled?

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16
Q

What is it important to as women of reproductive age in POA?

A

1) could they be pregnant?

2) when was their last menstrual period?

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17
Q

Water fasting period before anaesthetics?

A

up to 2 hours before induction of anaesthetic

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18
Q

Fasting period before anaesthetics for food or milk-containing products?

A

up to 6 hours before induction of anaesthetic

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19
Q

Chewing gum before anaesthetics?

A

Up to 2 hours before

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20
Q

What is the purpose of Wilson’s score?

A

Can indicate how difficult an airway will be.

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21
Q

What Wilson’s score suggests easy laryngoscopy?

A

<5

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22
Q

What Wilson’s score suggests potentially difficult laryngoscopy?

A

5-8

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23
Q

What Wilson’s score suggests indicates a risk of severe difficulty in laryngoscopy?

A

8-10

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24
Q

What score is used to predict the ease of endotracheal intubation?

A

The Mallampati score

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25
Q

What does the Mallampati test comprise?

A

The test comprises a visual assessment of the distance from the tongue base to the roof of the mouth, and therefore the amount of space in which there is to work.

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26
Q

What is involved in the ‘airway assessment’ in POA?

A

1) Wilson’s score

2) Mallampati score

3) Dentition e.g. caps, crowns, wobbly teeth

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27
Q

Does warfarin need to be stopped prior to surgery?

A

If minor superficial surgery e.g. ophthalmic or minor dental procedures) –> NO

For all other surgeroes –> the last dose of warfarin should be given 6 days before the procedure.

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28
Q

When should warfarin be stopped prior to surgery?

A

6 days

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29
Q

For emergency surgery or surgery where warfarin was not omitted, what should you check?

A

1) check INR

2) consider reversal with Vitamin K or other agents according to procedure and timeframe.

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30
Q

What do ‘bridging therapies’ refer to?

A

The use of alternative anticoagulation therapy, such as short-acting LMWH, during the pre- and immediately postoperative period.

See hospital protocol.

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31
Q

How is unfractionated heparin (UH) usually given?

A

is short-acting and normally given via IV infusion

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32
Q

How soon before a neuraxial block should heparin be stopped?

A

4 hours before (with evidence of a normal APTT)

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33
Q

Is UH or LMWH longer acting?

A

LMWH

34
Q

How is LMWH usually given?

A

Subcutaneous infusion

35
Q

Following “prophylactic dose LMWH”, how long must you wait before performing a neuraxial block?

A

12 hours

36
Q

Following “treatment dose LMWH”, how long must you wait before performing a neuraxial block?

A

24 hours

37
Q

Following prophylactic dose of Rivaroxaban, how long should you wait before neuraxial block?

A

18 hours (if creatinine clearance >30ml/min)

38
Q

Following treatment dose of Rivaroxaban, how long should you wait before neuraxial block?

A

48 hours

39
Q

How long must you wait before neuraxial block after dabigatran?

A

48 hours

40
Q

How long must you wait before apixaban block after dabigatran?

A

48 hours

41
Q

Must aspirin, dipyridamole and NSAIDs be stopped prior to surgery?

A

No - unless there are confounding factors such as deteriorating renal function.

42
Q

Which antiplatelet must be stopped before surgery and/or neuraxial intervention?

A

Clopidogrel

43
Q

When should clopidogrel be stopped prior to surgery? Why?

A

7 days: clopidogrel causes irreversible platelet inhibition

44
Q

When should ACEi be stopped prior to surgery?

A

should be withheld on the morning of major surgery.

45
Q

When should beta blockers be stopped prior to surgery?

A

Beta-blockers should be continued as per the patient’s normal prescription unless otherwise instructed.

46
Q

What tests do patients on digoxin require prior to surgery?

A

ECG and blood tests to exclude hypokalaemia.

47
Q

Should anticonvulsants be stopped prior to surgery?

A

No

48
Q

Should oral hypoglycaemic agents such as metformin be stopped prior to surgery?

A

should be omitted on the day of surgery.

49
Q

When should diabetic patients e considered for insulin-dextrose sliding scale therapy during the perioperative period?

A

Diabetic patients that will be missing more than one meal due to fasting and operative time

50
Q

Which patients will need supplementary steroids during the perioperative period?

A

Patients who take more than 5mg prednisolone daily

51
Q

Should the COCP be stopped prior to surgery?

A

Yes - VTE risk

52
Q

Should tamoxifen be stopped prior to surgery?

A

should only be stopped if the risk of VTE outweighs the risk of interrupting treatment.

53
Q

Should herbal medications such as St John’s Wort and ephedra be stopped prior to surgery?

A

Yes - 2 weeks before

54
Q

What medication can be given to minimise stomach acid and reduce the risk of aspiration during induction?

A

Antacids e.g. Ranitidine or omeprazole

55
Q

Give some examples of additional investigations that may be performed in the pre-operative period to ensure the patient is fit enough to undergo their operation?

A

1) ECG

2) Blood tests:
- FBC
- U&Es
- Creatinine
- Sickle cell test

3) Pregnancy test

4) Baseline CXR

5) Cardiopulmonary exercise testing (CPET)

56
Q

Under what circumstances should an ECG be performed in the pre-op period?

A

1) >80 y/o

2) >60y/o and surgical severity >3

3) Cardiovascular or renal disease

57
Q

When should a pregnancy test be performed in the pre-op period?

A

Should be performed in all women of reproductive age.

58
Q

What BP is required prior to operation?

A

The patient’s BP needs to be 160/100 mmHg or lower in the community prior to the operation.

If a patient’s BP is greater than 180mmHg systolic or 110mmHg diastolic on the day of surgery, the operation should be postponed until hypertension is under control

59
Q

What investigations should be considered prior to elective surgery?

A

1) Consider pre admission clinic to address medical issues.

2) Blood tests including FBC, U+E, LFTs,

3) Clotting, Group and Save

4) Urine analysis

5) Pregnancy test

6) Sickle cell test

7) ECG/ Chest x-ray

60
Q

Give some examples of clear fluids that are allowed up to 2 hours before surgery?

A
  • water
  • fruit squash WITHOUT pulp
  • coffee or tea WTIHOUT milk
  • ice lollies
61
Q

What does management of diabetes mellitus in the perioperative period depend on?

A

1) required duration of fasting

2) timing of surgery (morning or afternoon)

3) usual treatment regimen (insulin, antidiabetic drugs or diet)

4) prior glycaemic control

5) other co-morbidities

62
Q

What are diabetic patients at an increased risk of in surgery?

A

1) increased risk of wound & respiratory infections

2) increased risk of post-operative AKI

3) increased length of hospital stay

63
Q

Pre-op management of diabetic patients who are treated with insulin and have GOOD glycaemic control (HbA1c <69 mmol/mol) and undergoing MINOR procedures?

A

Can be managed during the operative period by adjustment of their usual insulin regimen.

64
Q

Management of diabetic patients who are undergoing surgery requiring a long fasting period of MORE THAN ONE missed meal or whose diabetes is poorly controlled?

A

will usually require a variable rate intravenous insulin infusion (VRIII)

65
Q

Management of diabetic patients who are only taking ORAL antidiabetic drugs?

A

Often managed by manipulating medication on DAY OF surgery (depending on drug).

There are some exceptions to this:

1) if more than one meal is to be missed

2) patients with poor glycaemic control

3) risk of renal injury (e.g. low eGFR, contrast being used)

In this case –> VRIII.

66
Q

How should metformin be altered prior to surgery?

A

Day prior –> take as normal

Day of (morning operation):
- If taken once or twice a day - take as normal
- If taken three times per day, omit lunchtime dose

Day of (afternoon operation):
- If taken once or twice a day – take as normal
- If taken three times per day, omit lunchtime dose

67
Q

How should sulfonylureas be altered prior to surgery?

A

Day prior –> take as normal

Day of (morning op):
- If taken once daily in the morning - omit the dose that day
- If taken twice daily - omit the morning dose that day

Day of (afternoon op):
- If taken once daily in the morning - omit the dose that day
- If taken twice daily - omit both doses that day

68
Q

How should DPP-4 inhibtiors (-gliptins) and GLP-1 analogues (-tides) be altered prior to surgery?

A

Keep taking as normal.

69
Q

Where should diabetic patients be put on the operation list?

A

First on list (morning) to minimise poor glucose control.

70
Q

All patients admitted to hospital should be individually assessed to identify risk factors for VTE development and bleeding risk.

Which MEDICAL patients (i.e. not surgical/trauma) are deemed at increased risk of developing a VTE?

A

If there is significant reduction in mobility for 3 days or more (or anticipated to have significantly reduced mobility).

71
Q

Which surgical/trauma patients are deemed at increased risk of developing a VTE?

A

1) hip/knee replacement

2) hip fracture

3) general anaesthetic and a surgical duration of over 90 minutes

4) surgery of the pelvis or lower limb with a general anaesthetic and a surgical duration of over 60 minutes

5) acute surgical admission with an inflammatory/intra-abdominal condition

6) surgery with a significant reduction in mobility

72
Q

General risk factors for VTE on admission?

A
  • active cancer/chemotherapy
  • aged over 60
  • known blood clotting disorder (e.g. thrombophilia)
  • BMI over 35
  • dehydration
  • one or more significant medical comorbidities (e.g. heart disease; metabolic/endocrine pathologies; respiratory disease; acute infectious disease and inflammatory conditions)
  • critical care admission
  • use of HRT or COCP
  • varicose veins
  • pregnant or less than 6 weeks post-partum
73
Q

Mechanical VTE prophylaxis?

A

1) Correctly fitted anti-embolism (aka compression) stockings (thigh or knee height)

2) An Intermittent pneumatic compression device

74
Q

Pharmacological VTE prophylaxis?

A

1) Fondaparinux sodium (SC injection)

2) LMWH e.g. enoxaparin

3) UH (used as an alternative to LWMH in patients with CKD)

75
Q

When would UH be used as pharmacological VTE prophylaxis in hospital?

A

Patients with CKD

76
Q

Stepwise VTE prophylaxis in hospital?

A

1) Medical patients deemed at risk of VTE are started on pharmacological VTE prophylaxis
- no contraindications
- VTE risk outweighs bleeding risk

2) High risk –> add anti-embolic stockings alongside the pharmacological methods.

77
Q

When should COCP/HRT be stopped prior to surgery?

A

4 weeks before

78
Q

For certain surgical procedures pharmacological VTE prophylaxis is recommended for all patients to reduce the risk of a VTE developing post-surgery.

What 3 procedures require post-op VTE prophylaxis?

A

1) Hip replacement

2) Knee replacement

3) Fragility fractures of the pelvis, hip and proximal femur

79
Q

What is the post-op VTE prophylaxis following an elective hip replacement?

A

LMWH for 10 days followed by aspirin (75 or 150 mg) for a further 28 days.

OR

LMWH for 28 days combined with anti-embolism stockings until discharge.

OR

Rivaroxaban.

80
Q

What is the post-op VTE prophylaxis following an elective knee replacement?

A

Aspirin (75 or 150 mg) for 14 days

OR

LMWH for 14 days combined with anti-embolism stockings until discharge

OR

Rivaroxaban

81
Q
A