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PHM 544 - Commonly Prescribed Medications 2 > Contraindications/Black Box Warnings - Pain/GU > Flashcards

Contraindications/Black Box Warnings - Pain/GU Flashcards

1
Q

Baclofen contraindications

A

Hypersensitivity

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2
Q

Buprenorphine/Naloxone contraindications

A

Hypersensitivity

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3
Q

Carisoprodol contraindications

A

Hypersensitivity; acute intermittent porphyria

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4
Q

Celecoxib contraindications

A

Asthma, urticaria, or allergic-type reaction following aspirin or other NSAID administration; CABG surgery, treatment of perioperative pain, hypersensitivity to sulfonamides

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5
Q

Codeine/Acetaminophen contraindications

A

Hypersensitivity, use in age < 12 y of age, use in age 12-18 y postoperatively after tonsillectomy

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6
Q

Cyclobenzaprine contraindications

A

Hypersensitivity, concomitant MAOI use, heart failure, acute coronary phase of AMI, heart block, hyperthyroidism

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7
Q

Diclofenac contraindications

A

Hypersensitivity to diclofenac, concurrent ketorolac use, asthma, allergic type reaction following other NSAID use, CABG

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8
Q

Etodolac contraindications

A

Hypersensitivity; concurrent use of ketorolac or pentoxifylline; allergic-type reaction following NSAID; CABG surgery, treatment of perioperative pain

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9
Q

Fentanyl Transdermal contraindications

A

Acute or postoperative pain, bronchial asthma, hypersensitivity to fentanyl, mild or intermittent pain, opioid nontolerant patient, paralytic ileus

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10
Q

Hydrocodone (w/o acetaminophen) contraindications

A

Hypersensitivity, paralytic ileus, respiratory depression, severe asthma

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11
Q

Ibuprofen contraindications

A

Hypersensitivity, concurrent use with ketorolac or pentoxifylline; asthma, urticaria, or allergic-type reaction following aspirin or other NSAID administration; CABG surgery, treatment of perioperative pain

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12
Q

Indomethacin contraindications

A

Hypersensitivity, concurrent use with ketorolac or pentoxifylline; asthma, urticaria, or allergic-type reaction following aspirin or other NSAID administration; CABG surgery, treatment of perioperative pain

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13
Q

Lidocaine contraindications

A

Hypersensitivity

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14
Q

Meloxicam contraindications

A

Hypersensitivity; concurrent ketorolac, pentoxifylline use, asthma, allergic-type reaction following other NSAID use, CABG

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15
Q

Methadone contraindications

A

Bronchial asthma, hypersensitivity to opioids, paralytic ileus, respiratory depression, hypercarbia

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16
Q

Methocarbamol contraindications

A

Hypersensitivity

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17
Q

Morphine contraindications

A

Hypersensitivity to opioids, acute or severe asthma, paralytic ileus, respiratory depression, GI obstruction, concurrent use or use within 14 days of MAOI

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18
Q

Nabumetone contraindications

A

Hypersensitivity to nabumetone, other NSAIDs, aspirin, or sulfonamides; concurrent use of ketorolac, or pentoxifylline; asthma, CABG surgery

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19
Q

Naproxen contraindications

A

Hypersensitivity to naproxen, other NSAIDs, aspirin or sulfonamides; asthma or allergic-type reaction following aspirin or other NSAID administration, CABG surgery, treatment of perioperative pain

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20
Q

Oxycodone contraindications

A

Hypersensitivity to oxycodone or other opioids, asthma, paralytic ileus, respiratory depression, hypercarbia

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21
Q

Pentosan contraindications

A

Hypersensitivity

22
Q

Tramadol contraindications

A

Hypersensitivity to tramadol or other opioids, paralytic ileus, respiratory depression, bronchial asthma, age <12 y, hypercapnia, MAOI use or use within last 14 d

23
Q

Darifenacin contraindications

A

Hypersensitivity to darifenacin, gastric retention, glaucoma, urinary retention

24
Q

Dutasteride contraindications

A

Hypersensitivity to dutasteride, pregnancy, use in children

25
Q

Finasteride contraindications

A

Hypersensitivity to finasteride, pregnancy, or use in children

26
Q

Mirabegron contraindications

A

Hypersensitivity

27
Q

Oxybutynin contraindications

A

Hypersensitivity to oxybutynin, gastric retention, glaucoma, urinary retention

28
Q

Sildenafil contraindications

A

Hypersensitivity to phosphodiesterase inhibitors, concurrent nitrates, concurrent HIV protease inhibitors when used for treating pulmonary HTN, concurrent guanylate cyclase stimulators

29
Q

Solifenacin contraindications

A

Hypersensitivity to solifenacin, gastric retention, uncontrolled glaucoma, urinary retention

30
Q

Tadalafil contraindications

A

Hypersensitivity to phosphodiesterase inhibitors, concurrent nitrates, concurrent guanylate cyclase stimulators

31
Q

Tamsulosin contraindications

A

Hypersensitivity

32
Q

Tolterodine contraindications

A

Hypersensitivity to tolterodine or fesoterodine, gastric retention, uncontrolled narrow-angle glaucoma, urinary retention

33
Q

Vardenafil contraindications

A

Hypersensitivity to PDE inhibitors, concurrent use of nitrates and guanylate cyclase stimulators

34
Q

Phenazopyridine contraindications

A

Hypersensitivity and renal failure

35
Q

Baclofen BBW

A

Avoid abrupt discontinuation of oral or intrathecal product

36
Q

Celecoxib BBW

A

GI toxicity, cardiotoxicity, CABG

37
Q

Codeine/Acetaminophen BBW

A

Hepatotoxicity; Children who are CYP2D6 ultrarapid metabolizers; serious risks of misuse, abuse, addiction, overdose, and death; concurrent use with benzodiazepines; immediate release only, serious risk of misuse, accidental ingestion, neonatal opioid withdrawal syndrome

38
Q

Diclofenac BBW

A

Cardiovascular, GI risk, CABG

39
Q

Etodolac BBW

A

Cardiovascular and GI risk

40
Q

Fentanyl Transdermal BBW

A

Addiction, CYP 3A4/5 interactions, respiratory depression, fatalities in children, formulations not interchangeable, fever, care with disposal, REMS program, concurrent use with benzodiazepines or other CNS depressants, neonatal withdrawal, medication errors, heat exposure

41
Q

Hydrocodone (w/o acetaminophen) BBW

A

Addiction, abuse, misuse, REMS, respiratory depression, accidental ingestion, neonatal opioid withdrawal, alcohol, CYP3A4/5 interactions, hepatotoxicity, concurrent use with benzodiazepines

42
Q

Ibuprofen BBW

A

Cardiovascular events, GI toxicity, CABG

43
Q

Indomethacin BBW

A

Cardiovascular events, GI toxicity, CABG

44
Q

Meloxicam BBW

A

Cardiovascular thrombotic events, serious GI bleeding and perforation, CABG

45
Q

Methadone BBW

A

Accidental ingestion; addiction, abuse, and misuse; QTc prolongation; respiratory depression; concurrent use with benzodiazepines; REMS; neonatal opioid withdrawal; conditions for use in opioid addiction; CYP interactions

46
Q

Morphine BBW

A

Ethanol, addiction, abuse, and misuse, REMS, respiratory depression, neonatal opioid withdrawal, accidental ingestion, concurrent use with benzodiazepines, medication errors

47
Q

Nabumetone BBW

A

Thrombotic events; GI bleeding

48
Q

Naproxen BBW

A

Cardiovascular and GI risk; thrombotic events

49
Q

Oxycodone BBW

A

Addiction, abuse potential; REMS, respiratory depression, accidental ingestion, neonatal withdrawal, CYP3A4/5 interaction, concurrent use with benzodiazepines, medication errors with oral solution

50
Q

Tramadol BBW

A

Addiction, abuse, misuse, REMS, respiratory depression, accidental ingestions, CYP2D6 in children, neonatal withdrawal syndrome, drug interactions, concurrent benzodiazepines, medication errors, drug interactions with P450s

PHM 544 - Commonly Prescribed Medications 2 (28 decks)

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