Common and Rare/Severe AE - Neuro/Psych Flashcards

1
Q
A
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2
Q

Benztropine common ADRs

A

Constipation, nausea

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3
Q

Benztropine rare but serious ADRs

A

Anhidrosis, drug-induced psychosis, heat stroke, increased body temperature, tachycardia, visual hallucinations

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4
Q

Carbamazepine common ADRs

A

Hyponatremia, dizziness, nausea

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5
Q

Carbamazepine rare but serious ADRs

A

Cardiac dysrhythmia, hepatitis, nephrotoxicity, pancreatitis, pancytopenia, Stevens-Johnson syndrome, syncope, toxic epidermal necrolysis, suicidal thoughts, and behaviors

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6
Q

Carbidopa/Levodopa common ADRs

A

Dyskinesia

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7
Q

Carbidopa/Levodopa rare but serious ADRs

A

Orthostatic hypotension, neuroleptic malignant syndrome, hallucinations, sleep attacks, compulsive behaviors

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8
Q

Dexmethylphenidate common ADRs

A

Weight loss, loss of appetite, headache, insomnia, restlessness

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9
Q

Dexmethylphenidate rare but serious ADRs

A

AMI, seizures, spasmodic movement, anemia, stroke, thrombocytopenia, psychosis, mania, drug dependence, priapism

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10
Q

Divalproex common ADRs

A

Abdominal pain, alopecia, asthenia, diarrhea, diplopia, dizziness, headache, nausea, somnolence, tremor, vomiting

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11
Q

Divalproex rare but serious ADRs

A

Hepatitis, palpitation, pancreatitis, tachycardia, thrombocytopenia, suicidal ideation or behavior

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12
Q

Donepezil common ADRs

A

Asthenia

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13
Q

Donepezil rare but serious ADRs

A

Atrioventricular block, GI bleeding, torsades de pointes

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14
Q

Eletriptan common ADRs

A

Weakness

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15
Q

Eletriptan rare but serious ADRs

A

Angina, cardiac dysrhythmia, coronary arteriosclerosis, heart block, HTN, AMI, aphasia, cerebral ischemia, stroke, dystonia, hemiplegia, neuropathy, transient ischemic attack, oculogyric crisis

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16
Q

Eszopiclone common ADRs

A

Headache

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17
Q

Eszopiclone rare but serious ADRs

A

Anaphylaxis, angioedema

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18
Q

Gabapentin common ADRs

A

Dizziness, somnolence

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19
Q

Gabapentin rare but serious ADRs

A

Stevens-Johnson syndrome, suicidal thoughts

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20
Q

Guanfacine common ADRs

A

Drowsiness, headache, dizziness, insomnia, anorexia

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21
Q

Guanfacine rare but serious ADRs

A

Seizure, chest pain, rebound HTN

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22
Q

Lacosamide common ADRs

A

Dizziness, fatigue, ataxia, nausea, tremor, diplopia

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23
Q

Lacosamide rare but serious ADRs

A

Acute psychosis, bradycardia, hepatotoxicity, agranulocytosis, suicidality

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24
Q

Lamotrigine common ADRs

A

Rash, ataxia, somnolence, headache, diplopia, rhinitis, nausea, vomiting, insomnia

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25
Q

Lamotrigine rare but serious ADRs

A

Stevens-Johnson syndrome, anemia, leukopenia, disseminated intravascular coagulation, thrombocytopenia, liver failure, aseptic meningitis, suicidal thoughts

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26
Q

Levetiracetam common ADRs

A

Asthenia, fatigue, headache, somnolence, vomiting, increased BP

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27
Q

Levetiracetam rare but serious ADRs

A

Pancytopenia, hepatotoxicity, suicidal thoughts, suicide, Stevens-Johnson syndrome

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28
Q

Lisdexamfetamine common ADRs

A

Insomnia, irritability, loss of appetite, upper abdominal pain, xerostomia

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29
Q

Lisdexamfetamine rare but serious ADRs

A

Chest pain, new worsening existing psychotic disorders, AMI, stroke, sudden cardiac death, tachycardia, anaphylaxis, peripheral vasculopathy (including Raynaud’s), serotonin syndrome

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30
Q

Memantine common ADRs

A

None known

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31
Q

Memantine rare but serious ADRs

A

Stevens-Johnson syndrome, DVT, hepatitis, liver failure, cerebrovascular accident, grand mal seizure, transient ischemic attack, acute renal failure

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32
Q

Metaxalone common ADRs

A

Dizziness

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33
Q

Metaxalone rare but serious ADRs

A

Hemolytic anemia, leukopenia, jaundice, immune hypersensitivity reaction, maculopapular rash, slowed or difficult breathing when used in combination with opioids

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34
Q

Methylphenidate common ADRs

A

Weight loss, loss of appetite, headache, insomnia, irritability

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35
Q

Methylphenidate rare but serious ADRs

A

Seizures, spasmodic movement, anemia, thrombocytopenia, psychosis, mania, drug dependence, suicidal thoughts, priapism, peripheral vasculopathy

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36
Q

Modafinil common ADRs

A

Anxiety, headache, insomnia, nausea

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37
Q

Modafinil rare but serious ADRs

A

Cardiac dysrhythmia, Stevens-Johnson syndrome

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38
Q

Oxcarbazepine common ADRs

A

Somnolence, headache, diplopia, dizziness

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39
Q

Oxcarbazepine rare but serious ADRs

A

Anaphylaxis, angioedema, Stevens-Johnson syndrome, suicidal thoughts, pancytopenia

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40
Q

Phenobarbital common ADRs

A

None known

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41
Q

Phenobarbital rare but serious ADRs

A

Barbiturate withdrawal, bradyarrhythmia, megaloblastic anemia, respiratory depression, Stevens-Johnson syndrome

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42
Q

Phentermine common ADRs

A

Increased BP, palpitations, tachyarrhythmia, urticaria, constipation, diarrhea, xerostomia, dizziness, excitement, headache, insomnia, tremor, dysphoric mood, euphoria, restlessness

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43
Q

Phentermine rare but serious ADRs

A

Heart valve disorder, psychotic disorder, primary pulmonary HTN

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44
Q

Phenytoin common ADRs

A

Gingival hyperplasia

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45
Q

Phenytoin rare but serious ADRs

A

Hepatotoxicity, pancytopenia, systemic lupus erythematosus, Stevens-Johnson syndrome, suicidal behavior, withdrawal seizures

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46
Q

Pramipexole common ADRs

A

Asthenia, dream disorder, dyskinesia, extrapyramidal movements, nausea, somnolence

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47
Q

Pramipexole rare but serious ADRs

A

Blackouts, heart failure, impulsive behavior, melanoma

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48
Q

Pregabalin common ADRs

A

Dizziness, somnolence, ataxia, headache, peripheral edema

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49
Q

Pregabalin rare but serious ADRs

A

Angioedema

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50
Q

Rizatriptan common ADRs

A

None known

51
Q

Rizatriptan rare but serious ADRs

A

Angina, cardiac dysrhythmia, coronary arteriosclerosis, heart block, HTN, acute myocardial infarction, aphasia, cerebral ischemia, stroke, dystonia, hemiplegia, neuropathy, transient ischemic attack, oculogyric crisis

52
Q

Ropinirole common ADRs

A

Dizziness, dyskinesia, nausea, orthostatic hypotension, somnolence, vomiting, hallucinations

53
Q

Ropinirole rare but serious ADRs

A

Sinus node dysfunction, neuroleptic malignancy syndrome, impulse control/compulsive behaviors

54
Q

Topiramate common ADRs

A

Ataxia, loss of appetite, dizziness, impaired psychomotor performance, somnolence, fatigue, nystagmus, low serum bicarbonate

55
Q

Topiramate rare but serious ADRs

A

Erythema multiforme, Stevens-Johnson syndrome, hypohidrosis, increased body temperature, metabolic acidosis, liver failure, glaucoma, myopia, suicidal ideation, visual field defects

56
Q

Trazodone common ADRs

A

Dizziness, sedation, headache, nausea, somnolence, xerostomia

57
Q

Trazodone rare but serious ADRs

A

Bleeding risk, cardiac dysrhythmia, fractures, priapism, prolonged QTc, serotonin syndrome, suicidal thoughts, torsade de pointes

58
Q

Varenicline common ADRs

A

Dream disorder, nausea, headache, insomnia, irritability

59
Q

Varenicline rare but serious ADRs

A

Abnormal behavior, suicidal thoughts, angioedema, hypersensitivity reactions, increased risk of accidents, increased risk of cardiovascular related events, sleepwalking, seizures

60
Q

Zolpidem common ADRs

A

Dizziness, drowsiness, headache

61
Q

Zolpidem rare but serious ADRs

A

Tachycardia, complex behavior, abnormal thinking, behavior changes, anaphylaxis, worsening of depression, angioedema, drug dependence, slowed or difficult breathing when used in combination with opioids, falls leading to severe injuries associated with decreased level of consciousness, hallucinations

62
Q

Sumatriptan common ADRs

A

None known

63
Q

Sumatriptan rare but serious ADRs

A

Angina, cardiac dysrhythmia, coronary arteriosclerosis, heart block, HTN, AMI, aphasia, cerebral ischemia, stroke, dystonia, hemiplegia, neuropathy, transient ischemic attack, oculogyric crisis

64
Q

Amitriptyline common ADRs

65
Q

Amitriptyline rare but serious ADRs

A

Cardiac dysrhythmia, hepatotoxicity, seizures, suicidal thoughts

66
Q

Aripiprazole common ADRs

A

Akathisia, anxiety, extrapyramidal effects, headache, increased appetite, somnolence, weight gain, hyperglycemia

67
Q

Aripiprazole rare but serious ADRs

A

Slowed or difficult breathing when used in combination with opioids, compulsive behaviors, neuroleptic malignant syndrome, pancytopenia, QTc prolongation, seizures, suicidal thoughts, tardive dyskinesia

68
Q

Atomoxetine common ADRs

A

Abdominal pain, headache, insomnia, loss of appetite, nausea, weight loss, xerostomia

69
Q

Atomoxetine rare but serious ADRs

A

Dyskinesia, mania, prolonged QTc interval, psychotic disorders, seizure, suicidal thoughts, sudden cardiac death, tachycardia, hepatotoxicity

70
Q

Buspirone common ADRs

71
Q

Buspirone rare but serious ADRs

A

Mania, psychiatric disorder

72
Q

Bupropion common ADRs

A

Agitation, constipation, dizziness, headache, insomnia, nausea, tachyarrhythmia, tremor, xerostomia

73
Q

Bupropion rare but serious ADRs

A

Cardiac dysrhythmia, mania, seizure, suicidal thoughts, wide QRS complex

74
Q

Citalopram common ADRs

A

Constipation, dizziness, headache, insomnia, nausea, sedation, xerostomia

75
Q

Citalopram rare but serious ADRs

A

Prolonged QTc interval, serotonin syndrome, suicidal thoughts, torsades de pointes, agranulocytosis

76
Q

Clonazepam common ADRs

A

Ataxia, lethargy, somnolence, weight gain

77
Q

Clonazepam rare but serious ADRs

A

Seizures, mania, depression, withdrawal symptoms

78
Q

Desvenlafaxine common ADRs

A

Diaphoresis, dizziness, headache, nausea, xerostomia

79
Q

Desvenlafaxine rare but serious ADRs

A

GI hemorrhage, serotonin syndrome, suicidal thoughts

80
Q

Doxepin common ADRs

A

Xerostomia

81
Q

Doxepin rare but serious ADRs

A

Cardiac dysrhythmia, hepatotoxicity, suicidal thoughts

82
Q

Duloxetine common ADRs

A

Headache, nausea

83
Q

Duloxetine rare but serious ADRs

A

Hepatotoxicity, serotonin syndrome, suicidal thoughts

84
Q

Escitalopram common ADRs

A

Headache, nausea, sedation

85
Q

Escitalopram rare but serious ADRs

A

Prolonged QTc interval, serotonin syndrome, suicidal thoughts, torsades de pointes

86
Q

Fluoxetine common ADRs

A

Diarrhea, headache, insomnia, nausea, somnolence, tremor, xerostomia

87
Q

Fluoxetine rare but serious ADRs

A

Prolonged QTc interval, serotonin syndrome, suicidal thoughts, torsade de pointes, SIADH

88
Q

Lithium common ADRs

A

Cardiac dysrhythmias, fine tremor, hypothyroidism, leukocytosis, thrombocytosis, xerostomia

89
Q

Lithium rare but serious ADRs

A

Hypotension, nephrotoxicity, seizure, hypercalcemia, hyperparathyroidism

90
Q

Lurasidone common ADRs

A

Akathisia, extrapyramidal effects, headache, nausea, somnolence

91
Q

Lurasidone rare but serious ADRs

A

Abnormal dreams, angioedema, bradycardia, neuroleptic malignancy syndrome, pancytopenia, seizures, suicidal thoughts

92
Q

Mirtazapine common ADRs

A

Constipation, increased appetite, somnolence, xerostomia, increased serum cholesterol, weight gain

93
Q

Mirtazapine rare but serious ADRs

A

Neutropenia, suicidal thoughts, QTc prolongation, torsades de pointes

94
Q

Nortriptyline common ADRs

A

Constipation

95
Q

Nortriptyline rare but serious ADRs

A

Cardiac dysrhythmia, heart block, hepatotoxicity, seizures, suicidal thoughts

96
Q

Olanzapine common ADRs

A

Akathisia, asthenia, dizziness, hypercholesterolemia, hyperglycemia, increased appetite, increased prolactin levels, increased triglycerides, somnolence, tremor, weight gain, xerostomia, orthostatic hypotension, increased LFTs

97
Q

Olanzapine rare but serious ADRs

A

Neuroleptic malignant syndrome, pancreatitis, sudden cardiac death, suicidal thoughts, tardive dyskinesia, DRESS, slowed or difficult breathing when used in combination with opioids

98
Q

Paroxetine common ADRs

A

Abnormal ejaculation, asthenia, constipation, diarrhea, headache, insomnia, nausea, somnolence

99
Q

Paroxetine rare but serious ADRs

A

Serotonin syndrome, suicidal thoughts

100
Q

Quetiapine common ADRs

A

Agitation, headache, HTN, somnolence, weight gain, xerostomia

101
Q

Quetiapine rare but serious ADRs

A

Neuroleptic malignant syndrome, neutropenia, pancreatitis, sudden cardiac death, syncope, tardive dyskinesia, slowed or difficult breathing when used in combination with opioids

102
Q

Risperidone common ADRs

A

Extrapyramidal symptoms, insomnia, anxiety, fatigue, metabolic changes (hyperglycemia, dyslipidemia, weight gain, DM)

103
Q

Risperidone rare but serious ADRs

A

Neuroleptic malignant syndrome, pancreatitis, stroke, pancytopenia, sudden cardiac death, syncope, tardive dyskinesia, priapism, slowed or difficult breathing when used in combination with opioids, seizure, suicidal ideation or behavior

104
Q

Sertraline common ADRs

A

Diarrhea, fatigue, headache, insomnia, nausea

105
Q

Sertraline rare but serious ADRs

A

Serotonin syndrome, suicidal thoughts

106
Q

Venlafaxine common ADRs

A

Dizziness, headache, insomnia, nausea, somnolence, xerostomia, weakness

107
Q

Venlafaxine rare but serious ADRs

A

GI hemorrhage, hepatotoxicity, serotonin syndrome, suicidal thoughts

108
Q

Vilazodone common ADRs

A

Diarrhea, nausea, headache

109
Q

Vilazodone rare but serious ADRs

A

Hyponatremia, serotonin syndrome, suicidal ideation

110
Q

Ziprasidone common ADRs

A

Dizziness, extrapyramidal disease, headache, nausea, somnolence

111
Q

Ziprasidone rare but serious ADRs

A

Bone marrow depression, diabetes, neuroleptic malignant syndrome, prolonged QTc interval, syncope, tardive dyskinesia, torsades de pointes, DRESS, slowed or difficult breathing when used in combination with opioids

112
Q

Alprazolam common ADRs

A

Ataxia, lethargy, retrograde amnesia, somnolence, weight gain, change in appetite, constipation, fatigue, cognitive dysfunction, decreased libido

113
Q

Alprazolam rare but serious ADRs

A

Seizures, mania, depression, liver failure, Stevens-Johnson syndrome

114
Q

Diazepam common ADRs

A

Drowsiness, impaired motor coordination

115
Q

Diazepam rare but serious ADRs

A

Seizures, mania, depression, withdrawal symptoms, elevated liver function tests

116
Q

Lorazepam common ADRs

A

Drowsiness, impaired motor coordination, retrograde amnesia

117
Q

Lorazepam rare but serious ADRs

A

Seizures, mania, depression, withdrawal symptoms

118
Q

Temazepam common ADRs

A

Drowsiness, somnolence, impaired motor coordination

119
Q

Temazepam rare but serious ADRs

A

Complex behavior, anaphylaxis, worsening of depression, angioedema, drug dependence

120
Q

Triazolam common ADRs

A

Ataxia, lethargy, retrograde amnesia, somnolence, weight gain, change in appetite, constipation, fatigue, cognitive dysfunction, decreased libido

121
Q

Triazolam rare but serious ADRs

A

Seizures, mania, depression, liver failure, Stevens-Johnson syndrome

122
Q

Clobazam common ADRs

A

Constipation, drooling, ataxia, lethargy, respiratory infections, somnolence, fever

123
Q

Clobazam rare but serious ADRs

A

Depression, Stevens-Johnson syndrome, suicidal attempts, toxic epidermal necrolysis, DRESS syndrome