Common and Rare/Severe AE - Pain/GU Flashcards

1
Q

Baclofen common ADRs

A

Nausea, asthenia, dizziness, somnolence, confusion

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2
Q

Baclofen Rare but serious ADRs

A

Slowed or difficult breathing when used in combination with opioids, pneumonia, GI hemorrhage, seizure.

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3
Q

Buprenorphine/Naloxone common ADRs

A

Vasodilation, sweating, headaches, insomnia, constipation, GI distress, opioid withdrawal, dizziness

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4
Q

Buprenorphine/Naloxone Rare but serious ADRs:

A

Stevens-Johnson syndrome, physical dependence, tolerance, elevated liver functions tests, seizures.

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5
Q

Carisoprodol common ADRs

A

Drowsiness, dizziness

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6
Q

Carisoprodol Rare but serious ADRs:

A

Slowed or difficult breathing when used in combination with opioids, seizure, drug dependence, withdrawal symptoms upon discontinuation after chronic use.

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7
Q

Celecoxib common ADRs

A

HTN, headaches, GI distress, diarrhea

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8
Q

Celecoxib Rare but serious ADRs:

A

Stevens-Johnson syndrome, GI ulcers and bleeding, thrombosis, elevated liver functions, acute renal failure.

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9
Q

Codeine/Acetaminophen common ADRs

A

Nausea, vomiting, constipation, somnolence

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10
Q

Codeine/Acetaminophen Rare but serious ADRs:

A

Stevens-Johnson syndrome, GI bleeding, elevated liver functions, thrombocytopenia, physical dependence, tolerance, respiratory depression, serotonin syndrome, adrenal insufficiency, decreased sex hormones.

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11
Q

Cyclobenzaprine common ADRs

A

Xerostomia, headache, dizziness, drowsiness

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12
Q

Cyclobenzaprine Rare but serious ADRs:

A

Cardiac dysrhythmia, cholestasis, hepatitis, jaundice, anaphylaxis, immune hypersensitivity reaction, slowed or difficult breathing when used in combination with opioids.

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13
Q

Diclofenac common ADRs

A

Headaches, GI distress

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14
Q

Diclofenac Rare but serious ADRs:

A

Stevens-Johnson syndrome, GI bleeding, thrombosis, elevated liver functions, acute renal failure, MI, aplastic anemia, hemolytic anemia.

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15
Q

Etodolac common ADRs

A

None known

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16
Q

Etodolac Rare but serious ADRs:

A

Stevens-Johnson syndrome, GI bleeding, thrombosis, elevated liver functions, acute renal failure, congestive heart failure, aplastic anemia.

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17
Q

Fentanyl Transdermal common ADRs

A

Application site reactions, sweating, constipation, GI distress, confusion, headache, anxiety, urinary retention, fatigue

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18
Q

Fentanyl Transdermal Rare but serious ADRs:

A

Stevens-Johnson syndrome, physical dependence, tolerance.

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19
Q

Hydrocodone (w/o acetaminophen) common ADRs

A

Constipation, GI distress, somnolence

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20
Q

Hydrocodone (w/o acetaminophen) Rare but serious ADRs:

A

Stevens-Johnson syndrome, physical dependence, tolerance, respiratory depression, serotonin syndrome, adrenal insufficiency, decreased sex hormones.

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21
Q

Ibuprofen common ADRs

A

None known

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22
Q

Ibuprofen Rare but serious ADRs:

A

Stevens-Johnson syndrome, GI bleeding, thrombosis, elevated liver functions, acute renal failure, congestive heart failure, aplastic anemia.

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23
Q

Indomethacin common ADRs

A

Headache

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24
Q

Indomethacin Rare but serious ADRs:

A

Stevens-Johnson syndrome, GI bleeding, thrombosis, elevated LFTs, acute renal failure, heart failure, aplastic anemia.

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25
Q

Lidocaine common ADRs

A

Skin irritation, somnolence

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26
Q

Lidocaine Rare but serious ADRs:

A

Cardiac arrest, cardiac dysrhythmia, seizure, methemoglobinemia.

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27
Q

Meloxicam common ADRs

A

GI Distress

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28
Q

Meloxicam Rare but serious ADRs:

A

Stevens-Johnson syndrome, GI bleeding, elevated LFT, acute renal failure, congestive heart failure, aplastic anemia.

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29
Q

Methadone common ADRs

A

Constipation, GI distress, hypotension, dizziness, sedation

30
Q

Methadone Rare but serious ADRs:

A

Respiratory depression, arrhythmias, Stevens-Johnson syndrome, QTc prolongation, serotonin syndrome, adrenal insufficiency, hypogonadism.

31
Q

Methocarbamol common ADRs

A

Somnolence

32
Q

Methocarbamol Rare but serious ADRs:

A

Bradyarrhythmia, hypotension, syncope, leukopenia, anaphylactoid reaction, slowed or difficult breathing when used in combination with opioids.

33
Q

Morphine common ADRs

A

Constipation, nausea, vomiting, hypotension, dizziness, sedation, diaphoresis, headaches, depression, xerostomia

34
Q

Morphine Rare but serious ADRs:

A

Cardiac arrest, physical dependence, respiratory depression, serotonin syndrome, adrenal insufficiency, decreased sex hormones.

35
Q

Nabumetone common ADRs

A

Elevated LFTs, dyspepsia, abdominal pain, diarrhea

36
Q

Nabumetone Rare but serious ADRs:

A

Stevens-Johnson syndrome, GI bleeding, thrombosis, acute renal failure, congestive heart failure, aplastic anemia.

37
Q

Naproxen common ADRs

A

None known

38
Q

Naproxen Rare but serious ADRs:

A

Stevens-Johnson syndrome, GI bleeding, thrombosis, elevated LFTs, acute renal failure, congestive heart failure, aplastic anemia.

39
Q

Oxycodone common ADRs

A

Constipation, GI distress, sedation, sweating, pruritus

40
Q

Oxycodone Rare but serious ADRs:

A

Cardiac arrest, respiratory depression, physical dependence, tolerance, severe hypersensitivity, serotonin syndrome, adrenal insufficiency, decreased sex hormones.

41
Q

Pentosan common ADRs

42
Q

Pentosan Rare but serious ADRs:

A

Rectal hemorrhage, proctitis, thrombocytopenia.

43
Q

Tramadol common ADRs

A

Constipation, GI distress, dizziness, sedation, edema, sweating, pruritus, headaches, flushing

44
Q

Tramadol Rare but serious ADRs:

A

Cardiac arrest, physical dependence, tolerance, seizures, pancreatitis, suicidal ideation, anemia, serotonin syndrome, adrenal insufficiency, decreased sex hormones.

45
Q

Tizanidine common ADRs

A

Hypotension, xerostomia, asthenia, dizziness, somnolence, muscle weakness

46
Q

Tizanidine Rare but serious ADRs:

A

AMI, thrombocytopenia, hepatitis, PE, hypersensitivity, death, slowed or difficult breathing when used in combination with opioids.

47
Q

Darifenacin common ADRs

A

Constipation, xerostomia, blurred vision

48
Q

Darifenacin Rare but serious ADRs:

A

Angioedema.

49
Q

Dutasteride common ADRs

A

None known

50
Q

Dutasteride Rare but serious ADRs:

A

Heart failure, angioedema, allergic skin reactions, male breast cancer, prostate cancer (high grade).

51
Q

Finasteride common ADRs

A

Impotence, reduced libido

52
Q

Finasteride Rare but serious ADRs:

A

Heart failure, angioedema, allergic skin reactions, male breast cancer, prostate cancer (high grade).

53
Q

Mirabegron common ADRs

A

Hypertension

54
Q

Mirabegron Rare but serious ADRs:

A

Atrial fibrillation, angioedema, hallucinations, increased liver function enzymes.

55
Q

Oxybutynin common ADRs

A

Constipation, xerostomia, blurred vision

56
Q

Oxybutynin Rare but serious ADRs:

A

Prolonged QTc interval, seizures, tachycardia.

57
Q

Sildenafil common ADRs

A

Flushing, nausea, headache, visual disturbances, lack of blue/green color discrimination

58
Q

Sildenafil Rare but serious ADRs:

A

AMI, seizures, strokes, sudden hearing loss, priapism.

59
Q

Solifenacin common ADRs

A

Constipation, xerostomia, blurred vision

60
Q

Solifenacin Rare but serious ADRs:

A

Angioedema, QTc prolongation, exfoliative dermatitis.

61
Q

Tadalafil common ADRs

A

Flushing, nausea, myalgia, headache

62
Q

Tadalafil Rare but serious ADRs:

A

Stevens-Johnson syndrome, AMI, seizures, strokes, sudden hearing loss.

63
Q

Tamsulosin common ADRs

A

Dizziness, headache, abnormal ejaculation, rhinitis

Rare but serious ADRs: Retinal detachment, priapism.

64
Q

Tamsulosin Rare but serious ADRs:

A

Retinal detachment, priapism.

65
Q

Tolterodine common ADRs

A

Xerostomia

66
Q

Tolterodine Rare but serious ADRs:

A

Tachycardia, QTc prolongation, angioedema, hallucinations.

67
Q

Vardenafil common ADRs

A

Flushing, headache

68
Q

Vardenafil Rare but serious ADRs:

A

Acute myocardial infarction (AMI), seizures, strokes, sudden hearing loss, priapism, nonarteritic anterior ischemic optic neuropathy (NAION).

69
Q

Phenazopyridine common ADRs

70
Q

Phenazopyridine Rare but serious ADRs:

A

Anaphylaxis, methemoglobinemia, hemolytic anemia, hepatotoxic, nephrotoxicity.