Complement Chuchu Flashcards

1
Q

: most abundant complement

A

C3

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2
Q

; second most abundant complement

A

C4

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3
Q

: most potent opsonin

A

C3b

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4
Q

; most potent chemotaxin

A

C5a

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5
Q

: anaphylatoxins

A

• C3a, C4a, C5a

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6
Q

• Most common complement deficiency:

A

C2 deficiency

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7
Q

• Second deficiency that occurs with frequency:

A

MBL deficiency

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8
Q

• Most severe complement deficiency:

A

C3 deficiency

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9
Q

MASP-1: Homologous to

A

C1r

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10
Q

MASP-2: Homologous to

A

C1s

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11
Q

“MASP:

A

MBL-associated serine proteases

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12
Q

SLE - like syndrome, recurrent infections

A

C1

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13
Q

SLE - like syndrome, recurrent infections, atherosclerosis

A

C2

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14
Q

Severe recurrent infections, glomerulopathies

A

C3

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15
Q

SLE - like syndrome

A

CA

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16
Q

Neisseria syndrome

A

C5- C8

17
Q

Neisseria syndrome

A

C5- C8

18
Q

No known disease association

A

C9

19
Q

No known disease association

A

C9

20
Q

Hereditary angloedema

A

C1 INH

21
Q

No known disease association

A

C9

22
Q

Recurrent bacterial infections; glomerulopathies, atypical
Hemolytic Uremic Syndrome

A

Factor H or Factor I