Antibody Melvin Huhu Flashcards
Antibodies are specific proteins referred to as_____ isolated from______ fraction of protein by electrophoresis)
immunoglobulins
gamma globulin
GENERAL FUNCTIONS OF IMMUNOGLOBULINS
• Neutralize toxic substances
• Facilitate phagocytosis and kill microbes
• Combine with antigens on cellular surfaces
• Immunoglobulins are considered to be a humoral branch of immune response
• Structurally all antibodies are immunoglobulins but functionally not all immunoglobulins are antibodies
PROPERTIES OF ANTIBODIES
Protein in nature
With high molecular weight
Present in serum/plasma, saliva, semen, CSF, and other body
The diversity in antibody molecules arises from the______ regions which can undergo ________and______ during the immune response
variable
GENETIC RECOMBINATION
SOMATIC HYPERMUTATION