Common Patient Medications Flashcards
Anticoagulants medications
Xarelto Pradaxa Eliquis Coumadin Heparin
Anticoagulant function
Prevents clot formations
Reduces likelihood of clots enlarging
Prevent first or recurrent occlusive events
No thromboyltic effect (not clot busters)
What is the difference between coumadin and xarelto, pradaxa, eliquis and heparin?
Xarelto, pradaxa, eliquis and heparin target a specific clotting mechanism while coumadin is difficult to regulate.
Platelet aggregate inhibitors medications
Aspirin Plavix (clopidogrel) Effient (prasugrel) Brilinta (ticagrelor) "grel" DAPT-asa+P2Y12 inhibitor, MI stents, CABG (coronary artery bypass graft)
Platelet aggregate inhibitors purpose
Prevent recurrent clotting
Prevent clot englargement
Decrease likelihood of plaque build up
No thrombolytic effect
“grel” is associated with
antiplatelete
Angiotension converting enzyme (ACE) inhibitor medications
Zestril (lisinopril) Lotensin (benzapril) Capoten (captopril) Vasotec (enalapril) "pril"
“pril” is associated with
Angiotension converting enzyme (ACE) inhibitor
Angiotension converting enzyme (ACE) inhibitor function
Lowers levels of angiotensin II which leads to vasodilation
Treats hypertension and heart failure
How to Angiotension converting enzyme (ACE) inhibitor work?
Way to regulate blood pressure is through kidneys. If BP drops, kidneys release renin. Renin seeks out angiotensinogen. ACE is floating around and does not like angiotensinogen. Renin grabs angiontensinogen and changes it into angiotenion I. ACE likes angiotension I. Angiotension I meets up with ACE and becomes angiotension II. Goes to walls of vessels where there are receptors which cause vasoconstriction which leads to an increase in BP. If have high BP, can get medication to inhibit ACE. ACE and angiotension I are less likely to make angiotenion II and prevents vasoconstriction
Angiotension II receptor blocker (ARBs) medication
Atacand (candesartan) Cozaar (Losartan) Diovan (Valsartan) Micardis (telmisartan) "sartan"
Sartan is associated with
Angiotension II receptor blocker (ARBs)
Angiotension II receptor blocker (ARBs) function
Competitive inhibitor for angiotension II
Hypertension and heart failure
Sits on receptor of the vessels blocking angiotension II so vasodilate
Angiotensin receptor neprilysin inhibitor (ARNIs) medication
Entresto (sacubitril+valsartan)
What is neprilysin?
Enzyme that breaks down naturally occuring vasodilators. So ARNI inhibits neprilysin so will continue to vasodilate