cocci pt 3 Flashcards
What are the two main Neisseria bacteria?
how can you test them?
1) N. gonorrheoea
* ferments maltose
2) N. meningitidis
* does not ferment
What are the characteristics of Neisseria?
- Morphology
- ocygen requirements
- environmental resistance
Gram (-) diplococci
Aerobic
Not very resistant
What type of media can Neisseria grow on?
Enriched media (chocolate agar)
What virulence factors do Neisseria gonorrhea have?
what are their purposes?
Fimbriae (for attachment)
Protease (destroys IgA)
What type of disease is N. gonorrhea?
- Sexually transmitted disease
- Reportable
How can you identify N. gonorrhea?
Stain neutrophils from affected area.
(live inside)
What is the treatment for N gonorrhea?
Combination therapy of
Ceftriaxone
Azithromycin
What virulence factors do N. meningitidis contain?
- Fimbriae
- LPS endotoxin
- Protease
What two disease do N meningitidis cause?
Meningococcemia (infect bloodstream)
Meningitis (crosses blood brain barrier)
What are the effects of Meningococcemia?
Cytokines damage vascular system
How can you identify N. meningitidis?
Stain cerebrospinal fluid/blood
What are the treatments for N. meningitidis?
Cephalosporin
Conjugation vaccine
