Closer Look at Replication (2/3) Flashcards
DNA Polymerase Function
DNA polymerase is an enzyme that brings free floating nucleotides into the replication fork and pairs them with their complementary bases ( A = T ) ( C =- G)
What is considered the heart of replication and define it
Heart of replication is elongation, Elongation is the process of joining nucleotides to extend a new strand of DNA.
Where is Elongation located?
Both leading and lagging strands, it is contionous on the leading strand and discontinious on the lagging strand.
What is the exception with DNA Polymerase and what is the solution?
DNA Polymerase is only able to add nucleotides to an already existing chain, it cannot create a new one. Therefore it adds to an RNA strand as it is the first one produced during DNA synthesis.
What is the RNA chain called?
Primer and it gets synthesized by the primase.
After the synethesizing of the primer, what happens?
DNA can start building from the RNA primer at the 3’ end. (The lagging strand).