Clinical Tests & Conditions: WBC Flashcards
WBC Count
Numbers of WBC in a sample; should be 5,000-9,000 WB
WBCs/mm3
Differential WBC
Individual numbers of neutrophils, basophils, eosinophils, monocytes and lymphocytes in a blood sample.
Leukocytosis
greater than 10,000 WBC/mm3;
When does Leukocytosis occur?
pregnancy, post exercise, fractures, burns, illness, infection
Leukopenia
Less than 5,000 WBC/mm3
When does leukopenia occur?
radiation/chemotherapy, anemia, autoimmune diseases, bone marrow diseases, HIV/AIDS
Thrombocythemia
high number of platelets
causes of thrombocythemia
proliferative issues of bone marrow ,inflammation, decreased spleen function
Thrombocytopenia
low number of platelets
What causes thrombocytopenia?
genetic disorders, leukemia, infections, vb12 deficiency, autoimmune disorders.
Hemophilia
a deficiency, congenital, of one or more clotting factors
Von Willebrand’s disease
a deficiency of Von Willebrand’s factor. (congenital)
How do we treat hemophilia and von Willebrand’s disease?
give frozen or fresh plasma
DIC
Disseminated intravascular coagulopathy. An overwhelming activation and consumption of clotting factors and platelets, followed by enhanced fibrinolysis
What causes acquired coagulation disorders?
liver disease, vitamin K deficiency, coumarin toxicity, DIC
