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Gastrointestinal 2 > Clinical- IBD > Flashcards

Clinical- IBD Flashcards

1
Q

Rapid Fire: I will say a characteristic of a disease and you will tell me whether it’s crohns or ulcerative colitis. Ready?

Located anywhere in the GI tract

A

crohns

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2
Q

Continuous lesion

A

Ulcerative colitis

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3
Q

Rarely have strictures

A

Ulcerative colitis

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4
Q

Fistulas present

A

crohns

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5
Q

Only in colon

A

ulcerative colitis

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6
Q

skipping lesion

A

crohns

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7
Q

Fewer bowel movements, less bleeding, and more abd pain

A

crohns

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8
Q

No fistulas

A

ulcerative colitis

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9
Q

Common strictures

A

corhns

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10
Q

Frequent bloodly bowel movements with minimal abdominal pain.

A

ulcerative colitis (UC)

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11
Q

What % of patients with IBD have arthritis?

A

10-20%

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12
Q

What HLA-B27 disease is IBD assocaited with?

A

Akylosing Spondylitis

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13
Q

What % of IBD patients present with erythema nodosum, apthous ulcers, or pyoderma gangenosum?

A

10%

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14
Q

What % of patients present with episcleritis or uveitis?

A

5%

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15
Q

What % of IBD patients present with primary sclerosing cholangitis?

A

5%

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16
Q

What can form in the kidneys in crohns?

A

calcium oxalate stones

17
Q

What can form in the kidneys in UC?

A

uric acid stones (due to dehydration)

18
Q

Case: an IBD pt comes in with elevated alkaline phosphatase. What disease is this pt most likely experiencing?

A

Primary sclerosing colangitis

literally meaning hardening of the bile duct

19
Q

Which antiinflammatory can be given for the treament of mild-moderate UC?

A

sulfasalazine

20
Q

Which 2 drugs are the 5-ASA class?

A

Mesalamine + Olsalazine

“MO money MO problems”

21
Q

In what form of administration of aminosalcylates would u use for proctitis + L-sided colitis?

A

tropical (i.e. suppository)

22
Q

What route of administration you u use for Asacol + pentasa for pancolitis?

A

oral

gig.itty.goo.

23
Q

In what stage of UC would you give prednisone?

A

When it has progressed to pancolitis

24
Q

You shouldn’t exceed what dose of prednisome every 5 days for treating UC?

A

5mg

25
Q

Why can’t u give opiates in chronic UC patients?

A

cuz they can cause toxic megacolon

whenever i see megacolon i think of the massive terd episode of south park.

26
Q

When is the criteria for performing a colectomy in a UC pt?

A

when they have severe tintractable idsease, acute life threatening complication, colon stricture, or colon cancer

27
Q

True or False: sulfasalazine maintains remission in chrons as it does in UC.

A

False.

28
Q

Ture or False: sulfasalazine does not ahve additive effects or sparing effects when given with corticosteroids for crohns.

A

true

29
Q

True or false: sulfasalazine is not effective as prophylaxis in crohns.

A

True

30
Q

Budesone is a corticosteroid to treat what type of crohns?

A

mild-mod small bowel + colon crohns

31
Q

Which 2 drugs are good for maintenance therapy in crohns?

A

6-MP and Azathoprine

32
Q

What is the chemical structure of 6-MP relative to azathioprine?

A

6-MP is the active metabolite of azathioprine

33
Q

Why is 6-MP + azathioprine good to use with steroids?

A

Cuz u can lower the dose of steroids

34
Q

Metronidazole treats CD in what part of the GI tract?

A

Perianal

35
Q

How long does it take for metronidazole to start showing it’s effects?

A

6 weeks. THATS A LONG ASS TIME.

36
Q

Which drug is used in CD because it’s a TNF-alpha antibody?

A

infliximab (remicade)

37
Q

What type of chrons does a pt need to have to treat with infliximab?

A

fistulizing crohns

38
Q

What is the role of infliximib, as far as treating Sx, in CD?

A

maintians remission

Gastrointestinal 2 (13 decks)

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