Clinical- Amyloidosis/Misc/CIPO Flashcards
This type of amyloidosis is when there is diffuse deposition of amophous complexes in the tissues.
Systemic amylodiosis
Which layers of the intestines does the amyloid complexes deposit?
mucous membranes and msucle layers
So what are the problems since they deposit in the mudcle layers?
motility and malabsorbtion –> ulcers/bleeding
What are the additional Sx to amyloidosis (think tongue, liver, heart, blood and nerves)?
macroglossia, hepatomegaly, cardiomegaly, proteinuria, and peripheral neuropathy
protein deposits everywhere making shit big.
Radiography shows thickening of which anatomical structures of the bowel?
pilcae circulares
Which 2 tests confirms amyloidosis?
fat aspirate and rectal biopsy
What is the rule of 2’s for mekel’s diverticulum? (4 things)
2% of the population, is within 2 ft of the ileocecal valve, ~2 in long, symptomatic by age 2, and men > women
What can mekel’s diverticulum cause bleeding?
due to ulceration from ectopic gastric mucosa
This is a syndrome characterized by the clinical findings of mechanical bowel obstruction but without occusion of the lumen
pseudo-obstruction
What are the 2 main causes of idiopathic (primary) pseudo-obstruction?
visceral myopathy or neuropathy
What are the Sx to primary pseudo-obstruction?
recurrent attacks of N/V, cramping Abd pain, distenstion, and constipation. variable.
True or False: radiographic findings of primary pseudo-obstruction show a narrowing of the bowel.
FALSE. it shows dilation. essentially the bowel is stupid and can’t move poop. so it acts like a block but theres no block.
Amyloidosis, Parkinsons, myxedema, and antiparkinsonian meds (L-dopa) all contribute to the formation of what disease?
secondary pseudo-obstruction